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5-azidopentanoic acid N-hydroxysuccinimide ester is an important entity in the biomedical field and plays a key role. This compound has multiple uses as a catalyst for bioconjugation and protein labeling, triggering the specific binding of a drug or biomolecule to its intended receptor. This advantage ultimately facilitates the delivery of targeted drugs while refining diagnostic methods.
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-00411 | -- | $-- |
5-azidopentanoic acid N-hydroxysuccinimide ester, a versatile compound with diverse applications in biochemical and biotechnological fields, is the focus of the following applications presented with high perplexity and burstiness:
Protein Labeling and Bioconjugation: This ester serves as a cornerstone for labeling proteins using a click chemistry method, enabling the attachment of fluorescent tags or other molecules for visualization and tracking. By engaging with primary amines on proteins, it forms stable amide bonds, facilitating specific and sensitive labeling. This technique plays a crucial role in scrutinizing protein interactions, dynamics, and localization across various biological systems.
Drug Delivery Systems: Embracing the potential of 5-azidopentanoic acid N-hydroxysuccinimide ester leads to the modification of drug molecules or carriers, amplifying their targeting and delivery efficiency. By conjugating this ester to therapeutic agents, researchers can engineer prodrugs or targeted delivery systems that release active compounds precisely at disease sites. This strategy enhances therapeutic efficacy and reduces side effects significantly, particularly in cancer and targeted therapies.
Surface Functionalization: This compound assumes a pivotal role in surface functionalization processes involving nanoparticles, microarrays, and biosensors, enhancing detection and interaction with biological molecules. By integrating 5-azidopentanoic acid, surfaces can be customized to capture specific biomolecules or boost signal transduction. This application stands as a linchpin for the advancement of diagnostic tools, biosensors, and cutting-edge materials crucial for biomedical research.
Proteomics and Mass Spectrometry: Within the realm of proteomics, this ester finds utility in introducing azide groups into peptides and proteins, enabling their enrichment, separation, and identification. The azide-modified proteins can be selectively captured through click chemistry utilizing biotin or other affinity tags, facilitating their analysis via mass spectrometry. This methodology is imperative for studying post-translational modifications, protein-protein interactions, and the intricacies of complex biological systems.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
