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4-Formyl-N-(2-(naphthalen-2-yloxy)ethyl)benzamide is a linker for antibody-drug-conjugation (ADC).
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-00567 | -- | $-- |
4-Formyl-N-(2-(naphthalen-2-yloxy)ethyl)benzamide has shown potential in various pharmaceutical applications due to its unique chemical structure and biological activities. One prominent application is in the field of anti-cancer drug development. The compound has demonstrated activity in inducing apoptosis in cancer cells by interacting with specific cellular targets such as the tumor suppressor protein p53. By disrupting the function of p53, a protein known for its role in cell cycle regulation and apoptosis induction, 4-Formyl-N-(2-(naphthalen-2-yloxy)ethyl)benzamide can inhibit the growth of cancer cells and potentially reduce tumor progression. This makes it a promising candidate for further research and development as part of targeted cancer therapies.
Another critical application of 4-Formyl-N-(2-(naphthalen-2-yloxy)ethyl)benzamide is in neuroprotective drug research. Neurodegenerative diseases such as Alzheimer’s and Parkinson’s are characterized by the progressive loss of neuronal function and structure. The compound’s antioxidant properties can help protect neurons from oxidative stress, a key factor in the pathogenesis of these diseases. By mitigating oxidative damage, 4-Formyl-N-(2-(naphthalen-2-yloxy)ethyl)benzamide could help preserve neuronal integrity and function, potentially slowing down the progression of neurodegenerative disorders.
In the realm of anti-inflammatory treatments, 4-Formyl-N-(2-(naphthalen-2-yloxy)ethyl)benzamide displays significant potential. Chronic inflammation is a common underlying factor in many diseases, including arthritis, cardiovascular diseases, and chronic obstructive pulmonary disease (COPD). The compound’s ability to modulate inflammatory pathways and reduce the production of pro-inflammatory cytokines makes it a valuable candidate for developing new anti-inflammatory drugs. By attenuating inflammation, it could provide therapeutic benefits in managing and treating chronic inflammatory conditions.
Finally, 4-Formyl-N-(2-(naphthalen-2-yloxy)ethyl)benzamide is being explored for its antimicrobial properties. Bacterial resistance to existing antibiotics is a growing global health concern, necessitating the discovery of new antimicrobial agents. This compound has shown effectiveness against various bacterial strains, including both Gram-positive and Gram-negative bacteria. By inhibiting bacterial growth and proliferation, 4-Formyl-N-(2-(naphthalen-2-yloxy)ethyl)benzamide holds promise for treating bacterial infections, especially those resistant to conventional antibiotics. Continued research could lead to the development of new antibiotics based on its structure and mechanism of action.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
