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6-O-2-Propyn-1-yl-D-galactose is a nonclaevable glycolinker for the functionalization of cytotoxic drugs and applications in antibody-drug conjugation.
| Catalog Number | Size | Price | Quantity | ||
|---|---|---|---|---|---|
| BADC-00703 | -- | $-- | Inquiry |
6-O-2-Propyn-1-yl-D-galactose is a synthetic carbohydrate derivative with several specialized applications in bioscience. Here are some key applications of 6-O-2-Propyn-1-yl-D-galactose:
Glycobiology Research: This compound is often used in glycobiology to study carbohydrate-protein interactions. By incorporating 6-O-2-Propyn-1-yl-D-galactose into glycan structures, researchers can track and characterize glycosylation patterns on proteins. This assists in understanding how glycosylation affects protein function, stability, and cell signaling.
Metabolic Labeling: 6-O-2-Propyn-1-yl-D-galactose can be employed in metabolic labeling experiments to tag and visualize glycoproteins and glycolipids in cells. When introduced into cellular systems, this sugar analog integrates into glycosylation pathways, allowing for subsequent detection and imaging. This method is pivotal for mapping the spatial and temporal dynamics of glycosylated molecules.
Chemical Biology: In chemical biology, 6-O-2-Propyn-1-yl-D-galactose is used for bioorthogonal chemistry applications such as click chemistry. Its alkyne group allows for specific and efficient labeling reactions, facilitating the conjugation of probes or other functional groups. This enables detailed studies of molecular interactions and the creation of complex biomolecular assemblies.
Drug Delivery Systems: This carbohydrate derivative can be utilized in the design of targeted drug delivery systems. By attaching 6-O-2-Propyn-1-yl-D-galactose to therapeutic agents, researchers can exploit specific carbohydrate-recognition mechanisms to direct drugs to particular cells or tissues. This approach aims to enhance the efficacy and reduce the side effects of treatments.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
