DC10SMe

DC10SMe Catalog number: BADC-01385

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DC10SMe is a DNA alkylating agent useful in the synthesis of antibody drug conjugates (ADCs). DC10SMe has IC50 values of 15 pM, 12 pM and 12 pM against Ramos, Namalwa and HL60/s cancer cells, respectively.

Category
ADCs Cytotoxin
Product Name
DC10SMe
Catalog Number
BADC-01385
Molecular Formula
C35H29N5O4S2
Molecular Weight
647.77
DC10SMe

Ordering Information

Catalog Number Size Price Quantity
BADC-01385 -- $-- Inquiry
Description
DC10SMe is a DNA alkylating agent useful in the synthesis of antibody drug conjugates (ADCs). DC10SMe has IC50 values of 15 pM, 12 pM and 12 pM against Ramos, Namalwa and HL60/s cancer cells, respectively.
Synonyms
DC10SMe; CHEMBL2158589; AKOS040732934; HY-135122; CS-0109488
IUPAC Name
5-[3-(methyldisulfanyl)propanoylamino]-N-[2-[(13S)-8-oxo-11-azatetracyclo[8.4.0.01,13.02,7]tetradeca-2,4,6,9-tetraene-11-carbonyl]-1H-indol-5-yl]-1H-indole-2-carboxamide
Canonical SMILES
CSSCCC(=O)NC1=CC2=C(C=C1)NC(=C2)C(=O)NC3=CC4=C(C=C3)NC(=C4)C(=O)N5CC6CC67C5=CC(=O)C8=CC=CC=C78
InChI
InChI=1S/C35H29N5O4S2/c1-45-46-11-10-32(42)36-22-6-8-26-19(12-22)14-28(38-26)33(43)37-23-7-9-27-20(13-23)15-29(39-27)34(44)40-18-21-17-35(21)25-5-3-2-4-24(25)30(41)16-31(35)40/h2-9,12-16,21,38-39H,10-11,17-18H2,1H3,(H,36,42)(H,37,43)/t21-,35?/m1/s1
InChIKey
LMJIHUHQBTUVRR-HPUOVZDUSA-N
Density
1.5±0.1 g/cm3
Storage
Store at -20°C
Boiling Point
937.7±65.0°C at 760 mmHg
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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