Gly-Cyclopropane-Exatecan - CAS 2414254-49-0

Gly-Cyclopropane-Exatecan - CAS 2414254-49-0 Catalog number: BADC-01366

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Gly-Cyclopropane-Exatecan is a derivative of Exatecan. Exatecan is a drug which is a structural analog of camptothecin with antineoplastic activity and has been used in trials studying the treatment of Sarcoma, Leukemia, Lymphoma, Lung Cancer, and Liver Cancer, among others.

Category
ADCs Cytotoxin
Product Name
Gly-Cyclopropane-Exatecan
CAS
2414254-49-0
Catalog Number
BADC-01366
Molecular Formula
C32H34FN5O7
Molecular Weight
619.64
Gly-Cyclopropane-Exatecan

Ordering Information

Catalog Number Size Price Quantity
BADC-01366 -- $-- Inquiry
Description
Gly-Cyclopropane-Exatecan is a derivative of Exatecan. Exatecan is a drug which is a structural analog of camptothecin with antineoplastic activity and has been used in trials studying the treatment of Sarcoma, Leukemia, Lymphoma, Lung Cancer, and Liver Cancer, among others.
Synonyms
2-((2-aminoacetamido)methoxy)-2-cyclopropyl-N-((1S,9S)-9-ethyl-5-fluoro-9-hydroxy-4-methyl-10,13-dioxo-2,3,9,10,13,15-hexahydro-1H,12H-benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinolin-1-yl)acetamide
IUPAC Name
2-[[(2-aminoacetyl)amino]methoxy]-2-cyclopropyl-N-[(10S,23S)-10-ethyl-18-fluoro-10-hydroxy-19-methyl-5,9-dioxo-8-oxa-4,15-diazahexacyclo[14.7.1.02,14.04,13.06,11.020,24]tetracosa-1,6(11),12,14,16,18,20(24)-heptaen-23-yl]acetamide
Canonical SMILES
CCC1(C2=C(COC1=O)C(=O)N3CC4=C5C(CCC6=C5C(=CC(=C6C)F)N=C4C3=C2)NC(=O)C(C7CC7)OCNC(=O)CN)O
InChI
InChI=1S/C32H34FN5O7/c1-3-32(43)19-8-23-27-17(11-38(23)30(41)18(19)12-44-31(32)42)26-21(7-6-16-14(2)20(33)9-22(36-27)25(16)26)37-29(40)28(15-4-5-15)45-13-35-24(39)10-34/h8-9,15,21,28,43H,3-7,10-13,34H2,1-2H3,(H,35,39)(H,37,40)/t21-,28?,32-/m0/s1
InChIKey
CEFSJFYTDCGHFB-XXCFHSPASA-N
Storage
Store at 0-4°C for short term (days to weeks) or -20°C for long term (months to years)
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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