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12-Azido-dodecanoyl-OSu is a click chemistry reagent that can be used as a hydrophobic bioconjugation linker.
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-01821 | -- | $-- |
12-Azido-dodecanoyl-OSu, a versatile synthetic reagent widely utilized in biochemical research and chemical biology, has diverse applications. Here are four key applications presented with high perplexity and burstiness:
Bioorthogonal Chemistry: Positioned at the forefront of bioorthogonal chemistry, 12-Azido-dodecanoyl-OSu plays a pivotal role in labeling and detecting biomolecules. Through selective attachment to proteins, lipids, or other molecules via azide-alkyne cycloaddition reactions, known colloquially as "click chemistry," researchers gain the ability to visualize and track biological processes within living cells sans disruption of native biochemistry.
Protein Modification: Facilitating indispensable site-specific protein modification, this compound empowers the study of protein function and interactions. By affixing 12-Azido-dodecanoyl-OSu to a specific amino acid residue, scientists can introduce probes or tags that streamline subsequent functional assays, fostering a deeper understanding of protein mechanisms and the development of innovative biotherapeutics.
Drug Delivery Systems: Pioneering advancements in targeted drug delivery systems, 12-Azido-dodecanoyl-OSu enables the design of sophisticated modalities for controlled release. Through conjugation with drug molecules or delivery vehicles like nanoparticles or liposomes, precise and targeted delivery to specific cells or tissues becomes achievable, thus enhancing therapeutic efficacy while minimizing off-target effects.
Surface Immobilization: In the interdisciplinary realms of material science and bioengineering, 12-Azido-dodecanoyl-OSu emerges as a cornerstone for surface immobilization of biomolecules. Leveraging its capacity to functionalize surfaces with azide groups, researchers can subsequently attach biomolecules through click reactions, galvanizing the creation of biosensors, diagnostic devices, and biointerfaces for diverse applications in biotechnology and medical research.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
