16-Iodo-2,5,8,11,14-pentaoxahexadecane is a linker widely used in antibody-drug conjugates (ADCs).
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BADC-01548 | -- | $-- | Inquiry |
16-Iodo-2,5,8,11,14-pentaoxahexadecane, a compound with exceptional chemical characteristics, finds diverse applications in the realm of bioscience. Here are four key applications presented with high perplexity and burstiness:
Radiolabeling: Playing a pivotal role in radiolabeling endeavors, 16-Iodo-2,5,8,11,14-pentaoxahexadecane is utilized for imaging and tracking studies. Through the substitution of the iodine atom with a radioactive isotope, researchers gain the ability to monitor the distribution and dynamics of the labeled molecule within biological systems. This technique proves invaluable for investigating pharmacokinetics, biodistribution, and receptor-ligand interactions.
Synthetic Chemistry: Serving as a crucial intermediate in organic synthesis, this compound facilitates the construction of intricate molecular architectures. Its iodine atom renders it a versatile precursor for various coupling reactions, such as Suzuki or Sonogashira couplings, empowering chemists to synthesize novel compounds with potential biological activities.
Drug Delivery Systems: Within the realm of drug delivery systems, 16-Iodo-2,5,8,11,14-pentaoxahexadecane plays a vital role, particularly in the design of liposomes and micelles. Thanks to its amphiphilic nature, the compound can interact with both hydrophilic and hydrophobic molecules, aiding in the encapsulation and targeted delivery of therapeutic agents. This capability enhances the bioavailability and efficacy of drugs, revolutionizing drug delivery strategies.
Polymer Chemistry: In the domain of polymer chemistry, this compound emerges as a valuable component capable of being incorporated as a monomer or functional group in the creation of advanced materials. Its unique structure presents opportunities for developing polymers with specific properties, such as enhanced solubility, biocompatibility, and responsiveness to stimuli. These innovative materials find applications in medical devices, coatings, and responsive hydrogels, showcasing the versatility and potential of 16-Iodo-2,5,8,11,14-pentaoxahexadecane in polymer science.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.