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NH2-PEG4-CH2CH2COOH is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-01144 | -- | $-- |
Amino-PEG4-propionic acid, a versatile reagent, finds application in diverse chemical and biological realms. Explore its key applications with a twist of high perplexity and burstiness:
Bioconjugation: Engage in bioconjugation marvels leveraging Amino-PEG4-propionic acid, a stellar performer in linking biomolecules like proteins or peptides with entities such as fluorophores or therapeutic marvels. The PEG4 spacer, introducing flexibility and mitigating steric hindrances, elevates the stability and functionality of the resulting conjugate. Witness this prowess in crafting cutting-edge diagnostic tools and precision-driven drug delivery conduits.
Drug Delivery: Enter the realm of drug delivery where Amino-PEG4-propionic acid shines in tailoring nanoparticle surfaces towards enhanced biocompatibility and circulation longevity. By embedding this reagent onto drug-laden nanoparticles, scientists unlock superior targeting precision and evade swift immune clearance. Embrace heightened therapeutic efficacy and diminished adverse effects in the realm of drug dispensation.
Polymer Chemistry: Unfold the potential of Amino-PEG4-propionic acid as a linchpin in crafting functionalized polymers essential for hydrogels, biocompatible coatings, and stimuli-responsive materials. The amino group's facile integration with diverse polymer frameworks, coupled with the PEG spacer's proffered hydrophilicity and suppleness, births materials boasting custom properties tailored for medical and industrial arenas.
Surface Modification: Dive into the widespread use of this compound in augmenting biomaterial surfaces to optimize their interaction with biological milieus. Witness how Amino-PEG4-propionic acid adorns implant surfaces, curbing protein adhesion and platelet interactions to elevate biocompatibility. Such modifications stand as pivotal milestones in the evolution of medical implements and the creation of tissue engineering masterpieces.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
