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Azide-C2-Azide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-01528 | -- | $-- |
Azide-C2-Azide, a multifaceted bifunctional linker, boasts a wide array of applications in chemical biology and materials science. Dive into the realm of Azide-C2-Azide with four high-perplexity, bursty applications:
Bioorthogonal Chemistry: Anchored in the foundation of modern bioorthogonal chemistry, Azide-C2-Azide plays a pivotal role in orchestrating bioorthogonal click chemistry reactions, most notably the copper-catalyzed azide-alkyne cycloaddition (CuAAC). This compound facilitates the precise and effective labeling of biomolecules within intricate biological systems without perturbing natural processes. Scientists harness this capability to mark and track proteins, nucleic acids, and other biomolecules with exceptional precision, ushering in novel avenues for molecular exploration.
Drug Delivery Systems: Spearheading drug delivery innovations, Azide-C2-Azide empowers the creation of intricate drug delivery systems by enabling the conjugation of therapeutic compounds to drug carriers. This bifunctional linker opens doors for coupling drugs to nanoparticles, liposomes, or other delivery platforms through click chemistry, enhancing targeted drug delivery and controlled release mechanisms.
Material Science: Within the domain of material science, Azide-C2-Azide stands out as a pivotal element in crafting functionalized polymers and surface coatings. By integrating azide groups into polymer structures or surface layers, scientists leverage click chemistry to affix diverse functional moieties, such as fluorescent tags or bioactive molecules. This methodical technique plays a vital role in formulating advanced materials with customizable properties, catering to applications in biotechnology and nanotechnology with unparalleled adaptability.
Proteomics: Navigating the intricate landscape of proteomics, Azide-C2-Azide emerges as a valuable tool for protein identification and characterization. By utilizing azide-functionalized probes to label proteins, researchers conduct pull-down assays and mass spectrometry analyses, shedding light on protein-protein interactions, post-translational modifications, and overall protein dynamics across diverse cellular contexts.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
