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Amino-PEG6-OH is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-01121 | -- | $-- |
Amino-PEG6-alcohol, a versatile bifunctional polymer, finds diverse applications in bioscience. Discover four key applications presented with a high degree of perplexity and burstiness:
Chemical Synthesis: Acting as a crucial linker in chemical synthesis, Amino-PEG6-alcohol facilitates the fusion of molecules together. Its bifunctional essence enables it to interact with amines and alcohols, serving as a valuable asset in constructing intricate bioconjugates. This utility propels the advancement of novel compounds in pharmaceutical and materials science, ushering in a new era of chemical innovation.
Drug Delivery: Within drug delivery systems, Amino-PEG6-alcohol plays a pivotal role in modifying the surfaces of nanoparticles and liposomes. This alteration bolsters the stability, solubility, and biocompatibility of delivery vehicles, elevating the efficacy and precision of drug transport. The process of PEGylation not only diminishes immunogenic responses but also prolongs the circulation duration of therapeutic agents, heralding a paradigm shift in drug delivery technology.
Protein Modification: Catalyst of protein modification, Amino-PEG6-alcohol acts as a reagent for the PEGylation of proteins, peptides, and various biomolecules. This process aids in augmenting the hydrodynamic radius, curbing proteolytic degradation, and mitigating immunogenicity of therapeutic proteins. PEGylated proteins frequently showcase enhanced pharmacokinetic properties, elevating their therapeutic potential and efficacy, thus redefining the landscape of protein-based therapies.
Surface Functionalization: In the realm of biomaterials, Amino-PEG6-alcohol lends its prowess to functionalize surfaces of medical implants and biosensors. The art of PEGylation imparts antifouling attributes, thwarting undesirable protein adsorption and cellular attachment. This enhancement fuels the biocompatibility and operational efficiency of medical tools and diagnostic apparatus, paving the way for cutting-edge advancements in healthcare technology.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
