(2R,4R)-H-D-Pro(4-N3)-OH hydrochloride - CAS 2737202-69-4

(2R,4R)-H-D-Pro(4-N3)-OH hydrochloride - CAS 2737202-69-4 Catalog number: BADC-01791

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(2R,4R)-H-D-Pro(4-N3)-OH (hydrochloride) is a click chemistry reagent containing an azide group.

Category
ADCs Linker
Product Name
(2R,4R)-H-D-Pro(4-N3)-OH hydrochloride
CAS
2737202-69-4
Catalog Number
BADC-01791
Molecular Formula
C5H9ClN4O2
Molecular Weight
192.60

Ordering Information

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BADC-01791 -- $--
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Description
(2R,4R)-H-D-Pro(4-N3)-OH (hydrochloride) is a click chemistry reagent containing an azide group.
Synonyms
(2R,4R) H-Pro(4-N3) HCl
IUPAC Name
(2R,4R)-4-azidopyrrolidine-2-carboxylic acid;hydrochloride
Canonical SMILES
C1C(CNC1C(=O)O)N=[N+]=[N-].Cl
InChI
InChI=1S/C5H8N4O2.ClH/c6-9-8-3-1-4(5(10)11)7-2-3;/h3-4,7H,1-2H2,(H,10,11);1H/t3-,4-;/m1./s1
InChIKey
BVURXEMVHARMIF-VKKIDBQXSA-N

(2R,4R)-H-D-Pro(4-N3)-OH hydrochloride, a specialized compound with diverse applications in research and pharmaceutical realms, offers unique opportunities for peptide synthesis, drug design, proteomics studies, and chemical biology. Here are four key applications showcased with a high degree of perplexity and burstiness:

Peptide Synthesis: Recognized for its role in peptide synthesis and peptidomimetics, (2R,4R)-H-D-Pro(4-N3)-OH hydrochloride plays a pivotal role in creating stable peptide bonds, fostering the development of bioactive peptides for therapeutic purposes. This compound serves as a critical tool in crafting peptides with enhanced stability and biological activity, unlocking new possibilities for peptide-based therapeutics.

Drug Design and Development: Positioned at the forefront of pharmaceutical research, (2R,4R)-H-D-Pro(4-N3)-OH hydrochloride contributes significantly to the design of novel drug candidates. Its integration into pharmaceutical compounds can bolster drug stability, bioavailability, and specificity, paving the way for the creation of medications with improved therapeutic profiles and diminished side effects, reshaping the landscape of drug development.

Proteomics Studies: An invaluable asset in proteomics research, (2R,4R)-H-D-Pro(4-N3)-OH hydrochloride facilitates the exploration of protein-protein interactions and structure-function relationships. By incorporating this compound into peptide sequences, researchers can probe how modifications impact protein activity and stability, offering profound insights into the dynamic world of proteins within biological systems, shedding light on their intricate functions.

Chemical Biology: At the intersection of chemistry and biology, (2R,4R)-H-D-Pro(4-N3)-OH hydrochloride acts as a foundational building block for synthesizing bioactive molecules. Featuring an azide group for facile conjugation with various biomolecules, this compound enables the creation of sophisticated chemical probes. These probes play a pivotal role in dissecting biological processes and pinpointing potential drug targets, empowering researchers to unravel the complexities of biological systems with precision and depth.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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