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NH2-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. NH2-PEG5-OH is also a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-01117 | -- | $-- |
Amino-PEG5-alcohol, a versatile reagent in bioconjugation and polymer chemistry, showcases diverse applications in biomedical research and biotechnology. Here are four key applications, each presented with a high degree of perplexity and burstiness:
Bioconjugation: By leveraging the unique properties of Amino-PEG5-alcohol, scientists intricately intertwine proteins, peptides, and various biomolecules, securing them to an array of surfaces or carriers. The incorporation of the PEG moiety not only enhances solubility and biocompatibility but also drives the advancement of targeted drug delivery systems and diagnostic tools to the forefront of innovation.
Surface Modification: Amino-PEG5-alcohol commands the spotlight in the art of surface modification, a critical technique applied to nanoparticles, medical implants, and biosensors. Through tailored adjustments to these surfaces, enhancing biocompatibility and minimizing nonspecific binding, the amino group facilitates covalent attachments to surface-active agents. This establishment of a hydrophilic barrier repels unwanted proteins and cells, optimizing the performance of medical devices and biosensors.
Polymer Synthesis: Within the intricate realm of polymer chemistry, Amino-PEG5-alcohol serves as a cornerstone for crafting specialized polymers with unique functionalities. The presence of amino and hydroxyl groups offers reactive hubs for subsequent chemical alterations and cross-linking reactions, paving the way for tailored polymers across a spectrum of applications, from hydrogels to drug delivery systems and tissue engineering scaffolds. This intricate polymerization process highlights the boundless versatility of Amino-PEG5-alcohol in the realm of polymer science, unlocking new horizons of material design.
Cell Culture Applications: Emerging as a pivotal tool within the domain of cell culture, Amino-PEG5-alcohol facilitates the engineering of surface functionalities that promote specific cellular adhesion and proliferation. Through the attachment of bioactive peptides or proteins onto PEGylated surfaces, researchers sculpt a controlled microenvironment conducive to cell growth, laying the groundwork for scientific breakthroughs in areas such as stem cell research and tissue engineering. This precision engineering of cellular behavior underscores the indispensable nature of Amino-PEG5-alcohol in orchestrating advancements at the forefront of scientific inquiry.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
