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Amino-PEG3-C2-acid is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-01159 | -- | $-- |
Amino-PEG3-propionic acid, a versatile chemical linker, is extensively utilized in bioconjugation and polymer chemistry. Here are four key applications presented with a high degree of perplexity and burstiness:
Protein Conjugation: At the intersection of chemistry and biology, Amino-PEG3-propionic acid plays a pivotal role in conjugating proteins, enzymes, or antibodies onto various surfaces or biomolecules. The incorporation of the polyethylene glycol (PEG) linker significantly boosts solubility, decreases immunogenicity, and enhances the stability and efficacy of protein conjugates. This application is indispensable in diagnostic assays and therapeutic agents, showcasing the intricate dance between chemistry and biology.
Drug Delivery Systems: In the realm of drug delivery systems, Amino-PEG3-propionic acid serves as a vital linker for attaching drug molecules to carrier systems such as nanoparticles or polymeric carriers. The presence of the PEG spacer extends circulation time, enhances drug bioavailability, and optimizes therapeutic impact. This sophisticated technique enables precise tissue targeting while minimizing adverse effects, marking a significant breakthrough in personalized medicine and targeted therapy.
Polymer Chemistry: A critical player in synthesizing functionalized polymers for diverse biomedical applications, Amino-PEG3-propionic acid empowers the design of polymers with tailored properties suitable for applications like tissue engineering, hydrogels, and advanced materials. By facilitating the introduction of functional groups at specific distances, this compound drives material science and biotechnology to new horizons, offering customized polymers with unique mechanical, chemical, and biological characteristics.
Surface Functionalization: Beyond its versatile applications, this compound finds utility in functionalizing surfaces such as nanoparticles, microchips, or biointerfaces with amino groups. The PEG linker acts as a shield against nonspecific binding and aggregation, elevating the specificity and sensitivity of surface-based assays. This application is at the core of biosensor development, diagnostic devices, and surface-coating technologies, illustrating the intricate interplay between chemistry, material science, and cutting-edge technology.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
