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NH2-PEG9-acid is a non-cleavable 9 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity | ||
|---|---|---|---|---|---|
| BADC-01154 | -- | $-- | Inquiry |
Amino-PEG8-propionic acid, a versatile compound with wide-ranging scientific and industrial applications, plays a pivotal role in various key areas. Here are four applications explored with high perplexity and burstiness:
Bioconjugation: A cornerstone of bioconjugation techniques, Amino-PEG8-propionic acid serves as a fundamental link between biomolecules (such as proteins, peptides, or nucleic acids) and surfaces or other molecules. Its PEGylated structure, fostering flexibility and solubility, mitigates steric hindrance and enhances biocompatibility. This feature is crucial for developing precise targeted drug delivery systems and diagnostic tools that promise groundbreaking advancements in personalized medicine.
Material Science: In the realm of material science, Amino-PEG8-propionic acid plays a pivotal role in the surface modification of nanoparticles, polymers, and other materials, boosting their functionality. Leveraging its hydrophilic properties, this compound aids in stabilizing colloidal suspensions and preventing nonspecific binding. Such applications are indispensable for creating cutting-edge materials with tailored properties, especially crucial in the realm of medical devices and nanotechnology, pushing the boundaries of scientific discovery.
Drug Delivery: A key player in drug delivery system design, Amino-PEG8-propionic acid is instrumental in enhancing the solubility and stability of pharmaceutical compounds. Through the conjugation of drugs with PEG chains, the pharmacokinetics and biodistribution of drugs undergo optimization, ultimately elongating the drug's circulation time and diminishing immunogenicity. This transformative approach elevates therapeutic efficacy, paving the way for more efficient and targeted drug delivery mechanisms.
Immunoassays: At the forefront of immunoassay preparation, Amino-PEG8-propionic acid plays a critical role in linking antigens or antibodies to assay surfaces, ensuring precise and sensitive detection of target molecules. PEGylation serves as a crucial tool in minimizing nonspecific interactions, thereby facilitating accurate and sensitive detection. The significance of this application is paramount in the development of diagnostic assays across medical, environmental, and food safety domains, ensuring heightened precision and reliability in various testing scenarios.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
