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Amino-PEG9-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-00897 | -- | $-- |
Amino-PEG9-propionic acid, a versatile compound with myriad scientific applications, finds its niche in bioconjugation, drug delivery, and molecular biology realms. Here are four key applications of Amino-PEG9-propionic acid:
Bioconjugation: A cornerstone in bioconjugation reactions, Amino-PEG9-propionic acid acts as a flexible spacer linking biomolecules like proteins, peptides, and antibodies. This spacer enhances solubility and diminishes steric hindrance between conjugated molecules, elevating the stability and functionality of resultant bioconjugates. Such optimized entities prove invaluable in diagnostic assays and therapeutic contexts, showcasing enhanced performance in diverse applications.
Drug Delivery Systems: Unveiling a revolutionary approach in drug delivery, Amino-PEG9-propionic acid plays a pivotal role in crafting polyethylene glycol (PEG)-ylated compounds that elevate drug pharmacokinetics. PEGylation, a game-changer, boosts drug solubility, curbs immunogenicity, and elongates drug circulation time in the bloodstream. Such enhancements pave the way for superior controlled release of therapeutic agents, promising enhanced efficacy and precision in drug delivery.
Surface Modification: In the arena of surface modification, Amino-PEG9-propionic acid emerges as a potent tool in transforming nanoparticles, medical devices, and biosensors. By leveraging the attachment of this compound to surfaces, one can forge biocompatible, non-fouling layers that repel protein adsorption and cell adhesion, ensuring surface purity and optimizing device performance. This characteristic is pivotal in advancing biomedical devices and refining biosensor efficiency to unprecedented levels.
Molecular Biology: Delving into molecular biology research, Amino-PEG9-propionic acid shines as a vital component in labeling nucleic acids with fluorescent dyes or other probes. The pliable PEG spacer facilitates precise, efficient labeling without disrupting nucleic acid hybridization properties.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
