t-Boc-N-amido-PEG2-bromide - CAS 165963-71-3

t-Boc-N-amido-PEG2-bromide - CAS 165963-71-3 Catalog number: BADC-00981

* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

t-Boc-N-amido-PEG2-bromide is a PEG linker containing a bromide group and a Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Category
ADCs Linker
Product Name
t-Boc-N-amido-PEG2-bromide
CAS
165963-71-3
Catalog Number
BADC-00981
Molecular Formula
C11H22BrNO4
Molecular Weight
312.20
Purity
≥95%
t-Boc-N-amido-PEG2-bromide

Ordering Information

Catalog Number Size Price Quantity
BADC-00981 -- $-- Inquiry
Description
t-Boc-N-amido-PEG2-bromide is a PEG linker containing a bromide group and a Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The Boc group can be deprotected under mild acidic conditions to form the free amine.
Synonyms
Br-PEG2-NHBoc; Boc-NH-PEG2-Br; BocNH-PEG2-CH2CH2Br; N-Boc-PEG2-bromide; tert-Butyl (2-(2-(2-bromoethoxy)ethoxy)ethyl)carbamate; 2-[2-(2-t-Boc-aminoethoxy]ethoxy]ethyl Bromide; N-[2-[2-(2-Bromoethoxy)ethoxy]ethyl]carbamic Acid 1,1-Dimethylethyl Ester; 2-[2-[2-(tert-Butoxycarbonylamino)ethoxy]ethoxy]ethyl Bromide; Carbamic acid, N-[2-[2-(2-bromoethoxy)ethoxy]ethyl]-, 1,1-dimethylethyl ester; N-Boc-2-[2-(2-bromoethoxy)ethoxy]ethanamine; 2-Methyl-2-propanyl {2-[2-(2-bromoethoxy)ethoxy]ethyl}carbamate
IUPAC Name
tert-butyl N-[2-[2-(2-bromoethoxy)ethoxy]ethyl]carbamate
Canonical SMILES
CC(C)(C)OC(=O)NCCOCCOCCBr
InChI
InChI=1S/C11H22BrNO4/c1-11(2,3)17-10(14)13-5-7-16-9-8-15-6-4-12/h4-9H2,1-3H3,(H,13,14)
InChIKey
WGWDCMKAMHBDPO-UHFFFAOYSA-N
Density
1.257±0.06 g/cm3 (Predicted)
Solubility
Soluble in Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Slightly)
Flash Point
185.3±23.7 °C
Index Of Refraction
1.472
LogP
1.75
PSA
60.28000
Vapor Pressure
0.0±0.9 mmHg at 25°C
Appearance
Pale Yellow Oily Matter
Quantity
Data not available, please inquire.
Shelf Life
-20°C 3 years powder; -80°C 2 years in solvent
Shipping
Room temperature, or blue ice upon request.
Storage
Store at -20°C under inert atmosphere
Boiling Point
382.8±27.0°C (Predicted)
Form
Liquid
Biological Activity
N-Boc-PEG3-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1] . In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Why Choose BOC Sciences?

Customer Support

Providing excellent 24/7 customer service and support

Project Management

Offering 100% high-quality services at all stages

Quality Assurance

Ensuring the quality and reliability of products or services

Global Delivery

Ensuring timely delivery of products worldwide

Questions & Comments
Verification code
Send Inquiry
Verification code
Resources & Supports
Inquiry Basket