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(2,5-dioxopyrrolidin-1-yl) 5-[[3-(2,5-dioxopyrrolidin-1-yl)oxycarbonyl-4-nitrocyclohexyl]disulfanyl]-2-nitrobenzoate is a linker for antibody-drug-conjugation (ADC).
![(2,5-dioxopyrrolidin-1-yl) 5-[[3-(2,5-dioxopyrrolidin-1-yl)oxycarbonyl-4-nitrocyclohexyl]disulfanyl]-2-nitrobenzoate](https://resource.bocsci.com/structure/924898-35-1.gif)
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-00706 | -- | $-- |
(2,5-dioxopyrrolidin-1-yl) 5-[[3-(2,5-dioxopyrrolidin-1-yl)oxycarbonyl-4-nitrocyclohexyl]disulfanyl]-2-nitrobenzoate, with its intricate structure, finds applications in specialized fields of biochemistry and molecular biology. Here are four key applications presented with high perplexity and burstiness:
Drug Delivery Systems: Acting as a pivotal linker, this compound facilitates the precise attachment of drugs to targeted delivery systems. By conjugating therapeutic molecules to this linker, medications can be delivered with pinpoint accuracy to specific tissues or cells, thereby enhancing their effectiveness and reducing potential side effects. This targeted approach is particularly advantageous in the realm of precision cancer therapy, where accuracy is paramount.
Protein Labeling: Within the realm of biochemical research, this compound serves as a valuable tool for protein labeling, enabling scientists to delve into protein dynamics and interactions. Through its interaction with specific amino acid residues in proteins, this compound acts as a visual marker for tracking and imaging studies, providing crucial insights into protein functionality and cellular processes.
Synthetic Chemistry: The versatility of (2,5-dioxopyrrolidin-1-yl) 5-[[3-(2,5-dioxopyrrolidin-1-yl)oxycarbonyl-4-nitrocyclohexyl]disulfanyl]-2-nitrobenzoate shines in the realm of synthetic chemistry, serving as a key player in the synthesis of complex molecules. Its functional groups can undergo diverse chemical reactions, making it a versatile intermediate in organic synthesis. This property enables the creation of novel compounds for both research and industrial applications, fueling advancements in chemistry.
Bioconjugation: Widely employed in the field of bioconjugation, this molecule facilitates the formation of stable linkages between biological molecules and synthetic compounds. By establishing disulfide bonds, it can connect antibodies or other proteins to fluorescent dyes, drugs, or other molecules, enabling a range of applications in drug development, diagnostic assays, and imaging studies. This technique lies at the core of interdisciplinary research at the intersection of biology and chemistry.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
