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(2S, 2'S)-Bis(2, 5-dioxopyrrolidin-1-yl)4, 4'-disulfanediylbis(2-acetamidobutanoate) is a linker for antibody-drug-conjugation (ADC).
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-00513 | -- | $-- |
(2S,2'S)-Bis(2,5-Dioxopyrrolidin-1-yl) 4,4'-Disulfanediylbis(2-Acetamidobutanoate) is a specialized chemical compound with diverse applications in biochemical research and biotechnology. Here are four key applications presented with high perplexity and burstiness:
Protein Cross-Linking: This compound serves as a pivotal protein cross-linking reagent, facilitating the exploration of intricate protein-protein interactions. By forging enduring covalent bonds among proteins, scientists delve into complex protein architectures and functionalities. This is indispensable for unraveling enzyme mechanisms and advancing the realm of protein-based therapeutics.
Bioconjugation: In the realm of bioconjugation protocols, (2S,2'S)-Bis(2,5-Dioxopyrrolidin-1-yl) 4,4'-Disulfanediylbis(2-Acetamidobutanoate) plays a crucial role in linking biomolecules like antibodies, peptides, or nucleic acids to diverse tags or carriers. This process enables the creation of targeted drug delivery systems, diagnostic assays, and imaging agents. The formation of stable conjugates elevates the specificity and efficacy of biomedical applications, revolutionizing targeted therapeutics.
Surface Modification: Employed in surface modification, this compound imparts specific biochemical properties to diverse surfaces. By tethering biologically active molecules to surfaces such as biosensors, medical implants, or cell culture materials, it enhances their operational capabilities. This application plays a pivotal role in the advancement of sophisticated biomedical devices and the creation of tissue engineering scaffolds, embodying the forefront of biomedical innovations.
Peptide Synthesis: In the realm of peptide chemistry, (2S,2'S)-Bis(2,5-Dioxopyrrolidin-1-yl) 4,4'-Disulfanediylbis(2-Acetamidobutanoate) acts as a potent coupling reagent, streamlining the formation of peptide bonds. By driving efficient coupling reactions, it facilitates the synthesis of intricate peptides and proteins. This process is indispensable for delving into protein structure, functionality, and propelling the development of peptide-based pharmaceuticals, thereby heralding a new era in therapeutic interventions.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
