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Biotin-PEG1-azide is an indispensable biochemical tool in the biomedical field and a multifaceted reagent for bioconjugation research in drug discovery and therapeutic research. Along with its ability to accurately and efficiently label biomolecules, especially proteins and nucleic acids, it facilitates subsequent analysis and targeting efforts.
| Catalog Number | Size | Price | Quantity | ||
|---|---|---|---|---|---|
| BADC-01524 | -- | $-- | Inquiry |
Biotin-PEG1-azide, a versatile reagent in bioconjugation and molecular biology with a myriad of applications. Here are four key applications of Biotin-PEG1-azide, presented with high perplexity and burstiness:
Protein Labeling: Leveraging Biotin-PEG1-azide, researchers frequently utilize click chemistry to biotinylate proteins. This process enables the attachment of proteins to streptavidin-coated surfaces for diverse assays such as ELISA and western blotting. The conjugation of biotin-PEG1-azide ensures minimal steric hindrance, preserving protein activity and functionality with precision.
Molecular Imaging: Within molecular imaging applications, Biotin-PEG1-azide plays a pivotal role. Biotinylated probes, detectable using fluorescent or radiolabeled streptavidin, offer insights into biological processes and enable the localization of target molecules within cells and tissues. This methodology proves particularly valuable in monitoring cell surface proteins and investigating real-time cellular dynamics.
Drug Delivery: The potential of Biotin-PEG1-azide extends to targeted drug delivery systems. By conjugating therapeutic agents to biotin-PEG1-azide, specific binding to biotin receptors on target cells is achieved, facilitating precise drug delivery. This targeted approach amplifies drug efficacy while minimizing off-target effects, culminating in enhanced therapeutic outcomes and improved patient care.
Affinity Purification: In the realm of biochemical research, Biotin-PEG1-azide finds application in affinity purification. Through affinity chromatography, biotinylated molecules can be purified using streptavidin-coated beads, offering high specificity in capturing and eluting biotin-tagged proteins, nucleic acids, or other biomolecules. This technique streamlines biochemical workflows, ensuring the preparation of high-purity biomolecular samples for advanced research endeavors.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
