Duocarmycin DM

Duocarmycin DM Catalog number: BADC-00722

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Duocarmycin DM is a DNA minor-groove alkylating agent, which can be used as an antibody drug conjugate (ADC) toxin. Duocarmycin DM is based on its characteristic curved indole structure and a spirocyclopropylcyclohexadienone electrophile to act anticancer activity.

Category
ADCs Cytotoxin
Product Name
Duocarmycin DM
Catalog Number
BADC-00722
Molecular Formula
C28H27ClF3N3O5
Molecular Weight
577.98
Purity
95%
Duocarmycin DM

Ordering Information

Catalog Number Size Price Quantity
BADC-00722 -- $-- Inquiry

Related Molecules

Description
Duocarmycin DM is a DNA minor-groove alkylating agent, which can be used as an antibody drug conjugate (ADC) toxin. Duocarmycin DM is based on its characteristic curved indole structure and a spirocyclopropylcyclohexadienone electrophile to act anticancer activity.
Synonyms
(S)-(1-(chloromethyl)-5-hydroxy-1,2-dihydro-3H-benzo[e]indol-3-yl)(5-(2-(dimethylamino)ethoxy)-1H-indol-2-yl)methanone TFA
IUPAC Name
[(1S)-1-(chloromethyl)-5-hydroxy-1,2-dihydrobenzo[e]indol-3-yl]-[5-[2-(dimethylamino)ethoxy]-1H-indol-2-yl]methanone;2,2,2-trifluoroacetic acid
Canonical SMILES
CN(C)CCOC1=CC2=C(C=C1)NC(=C2)C(=O)N3CC(C4=C3C=C(C5=CC=CC=C54)O)CCl.C(=O)(C(F)(F)F)O
InChI
InChI=1S/C26H26ClN3O3.C2HF3O2/c1-29(2)9-10-33-18-7-8-21-16(11-18)12-22(28-21)26(32)30-15-17(14-27)25-20-6-4-3-5-19(20)24(31)13-23(25)30;3-2(4,5)1(6)7/h3-8,11-13,17,28,31H,9-10,14-15H2,1-2H3;(H,6,7)/t17-;/m1./s1
InChIKey
DHKVELFKGGQACN-UNTBIKODSA-N
Shipping
Room temperature
Storage
Store at -20°C
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Historical Records: Duocarmycin DM
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