Nε-Azido-D-Lysine hydrochloride - CAS 1418009-93-4
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Nε-Azido-D-Lysine hydrochloride - CAS 1418009-93-4 Catalog number: BADC-01968

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Category
ADCs Linker
Product Name
Nε-Azido-D-Lysine hydrochloride
CAS
1418009-93-4
Catalog Number
BADC-01968
Molecular Formula
C6H13ClN4O2
Molecular Weight
208.60

Ordering Information

Catalog Number Size Price Quantity
BADC-01968 -- $--
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Synonyms
(R)-6-Azido-2-amino-hexanoic hydrochlorideD-Azidonorleucine hydrochloride; H-D-Lys(N3)-OH HCl; 6-Azido-D-norleucine HCl; N-epsilon-Azido-D-lysine HCl; 6-Azido-D-lysine hydrochloride
Melting Point
166-172°C
Appearance
White crystalline powder
Purity
≥ 99% (HPLC)
Storage
Store at 2-8 °C
1. 1-Haloacylpiperazines
S Groszkowski, J Sienkiewicz, L Korzycka Pol J Pharmacol Pharm. 1975 Apr-Jun;27(2):183-6.
By direct acylation of piperazine with halogenocarboxylic acid chlorides in acid medium, the hydrochlorides of 1-haloacylpiperazines were obtained.
2. Metal-free and regiospecific synthesis of 3-arylindoles
Chuangchuang Xu, Wenlai Xie, Jiaxi Xu Org Biomol Chem. 2020 Apr 8;18(14):2661-2671. doi: 10.1039/d0ob00317d.
A convenient, metal-free, and organic acid-base promoted synthetic method to prepare 3-arylindoles from 3-aryloxirane-2-carbonitriles and arylhydrazine hydrochlorides has been developed. In the reaction, the organic acid catalyzes a tandem nucleophilic ring-opening reaction of aryloxiranecarbonitriles and arylhydrazine hydrochlorides and Fischer indolization. The organic base triethylamine plays a crucial role in the final elimination step in the Fischer indole synthesis, affording 3-arylindoles regiospecifically. The reaction features advantages of microwave acceleration, non-metal participation, short reaction time, organic acid-base co-catalysis, and broad substrate scope.
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The dilution calculator equation

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Historical Records: Nε-Azido-D-Lysine hydrochloride
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