N-(Iodoacetamido)-Doxorubicin - CAS 114390-30-6

N-(Iodoacetamido)-Doxorubicin - CAS 114390-30-6 Catalog number: BADC-00892

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N-(Iodoacetamido)-Doxorubicin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Category
ADCs Linker
Product Name
N-(Iodoacetamido)-Doxorubicin
CAS
114390-30-6
Catalog Number
BADC-00892
Molecular Formula
C29H30INO12
Molecular Weight
711.45
Purity
98.0%

Ordering Information

Catalog Number Size Price Quantity
BADC-00892 -- $-- Inquiry
Description
N-(Iodoacetamido)-Doxorubicin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms
N-iodoacetyladriamycin
IUPAC Name
N-[(2S,3S,4S,6R)-3-hydroxy-2-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]-2-iodoacetamide
Canonical SMILES
CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)CO)O)NC(=O)CI)O
InChI
InChI=1S/C29H30INO12/c1-11-24(35)14(31-18(34)9-30)6-19(42-11)43-16-8-29(40,17(33)10-32)7-13-21(16)28(39)23-22(26(13)37)25(36)12-4-3-5-15(41-2)20(12)27(23)38/h3-5,11,14,16,19,24,32,35,37,39-40H,6-10H2,1-2H3,(H,31,34)/t11-,14-,16-,19-,24+,29-/m0/s1
InChIKey
SAGBOHNSGVDWII-MUTSDZRXSA-N
Solubility
10 mm in DMSO
Shelf Life
0-4 °C for short term (days to weeks), or -20 °C for long term (months).
Shipping
Room temperature
Storage
-20°C
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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