NH2-VC-PAB-DMEA-PNU159682 - CAS 2227350-96-9
  1. Home
  2. Products
  3. ADCs Cytotoxin with Linkers
  4. NH2-VC-PAB-DMEA-PNU159682

NH2-VC-PAB-DMEA-PNU159682 - CAS 2227350-96-9 Catalog number: BADC-01424

* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

NH2-VC-PAB-DMEA-PNU159682 is a sortase-reactive drug-linker conjugate used in the synthesis of antibody-drug conjugates (ADCs).

Category
ADCs Cytotoxin with Linkers
Product Name
NH2-VC-PAB-DMEA-PNU159682
CAS
2227350-96-9
Catalog Number
BADC-01424
Molecular Formula
C56H72N8O19
Molecular Weight
1161.22
Purity
≥95%
NH2-VC-PAB-DMEA-PNU159682

Ordering Information

Catalog Number Size Price Quantity
BADC-01424 -- $-- Inquiry

Featured Recommendations

Recommended Services
ADC Linkers Development Antibody Modification and Conjugation Technologies ADC Analysis and Characterization ADC Linker and Cytotoxin Conjugations ADC Payloads Development ADC Manufacture ADC Development for Targets ADC Development Platform
Description
NH2-VC-PAB-DMEA-PNU159682 is a sortase-reactive drug-linker conjugate used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms
VC-PAB-DMEA-PNU159682; L-Ornithinamide, L-valyl-N5-(aminocarbonyl)-N-[4-[11-[(2S,4S)-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-4-[[(1S,3R,4aS,9S,9aR,10aS)-octahydro-9-methoxy-1-methyl-1H-pyrano[4',3':4,5]oxazolo[2,3-c][1,4]oxazin-3-yl]oxy]-6,11-dioxo-2-naphthacenyl]-4,7-dimethyl-3,8,11-trioxo-2,9-dioxa-4,7-diazaundec-1-yl]phenyl]-; L-Valyl-N5-carbamoyl-N-(4-{4,7-dimethyl-3,8,11-trioxo-11-[(2S,4S)-2,5,12-trihydroxy-7-methoxy-4-{[(1S,3R,4aS,9S,9aR,10aS)-9-methoxy-1-methyloctahydro-1H-pyrano[4',3':4,5][1,3]oxazolo[2,3-c][1,4]oxazin-3-yl]oxy}-6,11-dioxo-1,2,3,4,6,11-hexahydro-2-tetracenyl]-2,9-dioxa-4,7-diazaundec-1-yl}phenyl)-L-ornithinamide
IUPAC Name
[2-oxo-2-[(2S,4S)-2,5,12-trihydroxy-7-methoxy-4-[[(2S,4R,6S,7S,9R,10S)-10-methoxy-6-methyl-5,8,11-trioxa-1-azatricyclo[7.4.0.02,7]tridecan-4-yl]oxy]-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]ethyl] N-[2-[[4-[[(2S)-2-[[(2S)-2-amino-3-methylbutanoyl]amino]-5-(carbamoylamino)pentanoyl]amino]phenyl]methoxycarbonyl-methylamino]ethyl]-N-methylcarbamate
Canonical SMILES
CC1C2C(CC(O1)OC3CC(CC4=C3C(=C5C(=C4O)C(=O)C6=C(C5=O)C(=CC=C6)OC)O)(C(=O)COC(=O)N(C)CCN(C)C(=O)OCC7=CC=C(C=C7)NC(=O)C(CCCNC(=O)N)NC(=O)C(C(C)C)N)O)N8CCOC(C8O2)OC
InChI
InChI=1S/C56H72N8O19/c1-27(2)43(57)50(71)61-33(11-9-17-59-53(58)72)49(70)60-30-15-13-29(14-16-30)25-79-54(73)62(4)18-19-63(5)55(74)80-26-37(65)56(75)23-32-40(47(69)42-41(45(32)67)44(66)31-10-8-12-35(76-6)39(31)46(42)68)36(24-56)82-38-22-34-48(28(3)81-38)83-51-52(77-7)78-21-20-64(34)51/h8,10,12-16,27-28,33-34,36,38,43,48,51-52,67,69,75H,9,11,17-26,57H2,1-7H3,(H,60,70)(H,61,71)(H3,58,59,72)/t28-,33-,34-,36-,38-,43-,48+,51+,52-,56-/m0/s1
InChIKey
BNWLMZKSKUNVSP-OLBIOUOSSA-N
Density
1.47±0.1 g/cm3
Boiling Point
1232.3±65.0°C at 760 mmHg
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Calculate
The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Calculate

Related Products

Azido-PEG4-Glu-Val-Cit-PAB-MMAE
Azido-PEG4-Glu-Val-Cit-PAB-MMAE
MC-Val-Cit-PAB-rifabutin
MC-Val-Cit-PAB-rifabutin
(CAS: 2055900-34-8)
VA-PAB-DMEA-PNU159682
VA-PAB-DMEA-PNU159682
(CAS: 2414872-62-9)
DOXO-EMCH
DOXO-EMCH
(CAS: 151038-96-9)
MC-Val-Cit-PAB-MMAE
MC-Val-Cit-PAB-MMAE
(CAS: 646502-53-6)
DGN549-C
DGN549-C
(CAS: 2058075-34-4)
Historical Records: DBCO-PEG4-Val-Cit-PAB-PNP | NH2-VC-PAB-DMEA-PNU159682
Why Choose BOC Sciences?

Customer Support

Providing excellent 24/7 customer service and support

Project Management

Offering 100% high-quality services at all stages

Quality Assurance

Ensuring the quality and reliability of products or services

Global Delivery

Ensuring timely delivery of products worldwide

Featured Services
cGMP Grade Products

BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
Site-Specific Conjugation

BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
Linkers for Bioconjugation

BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
ADC Targets
Questions & Comments
Verification code
Send Inquiry
Verification code
Resources & Supports
Inquiry Basket
loading Loading ......
Delete selectedGo to checkout