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3,6,9,12,15,18,21,24,27-Nonaoxanonatriacontan-1-ol is a linker widely used in antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-01541 | -- | $-- |
| NCT Number | Title | Condition Or Disease | Phase | Start Date | Sponsor | Status |
|---|---|---|---|---|---|---|
| NCT01185951 | TENDOSHOCK-2010 Combination Therapy for Athletic Tendinopathies | Tendinopathy | Phase 2 | January 2007 | Hannover Medical School | Unknown status |
| NCT02154789 | An Assessment of Intra-lesional 3% Polidocanol Solution in the Treatment of Digital Myxoid Cyst | Ganglion Cysts | Phase 4 | June 2014 | University of Edinburgh | Unknown status |
| NCT02462720 | COMFORT: A Multicenter, Open-label, Randomized, Crossover Study | Varicose Veins | Phase 4 | May 2015 | BTG International Inc. | Completed |
| NCT03257254 | Effect of VarIthena on Wound Healing in VLU | Venous Leg Ulcer | September 29, 2017 | Provensis Ltd | Recruiting |
3,6,9,12,15,18,21,24,27-Nonaoxanonatriacontan-1-ol, a versatile polyethylene glycol (PEG) derivative, finds applications across scientific and industrial realms. Here are four key applications portrayed with a high degree of perplexity and burstiness:
Drug Delivery Systems: Embracing this PEG derivative, pharmaceutical formulations undergo a metamorphosis, enhancing solubility and stability of drugs. This transformation extends the circulation time of therapeutic agents in the bloodstream, elevating their biodistribution and efficacy. Moreover, the molecule's presence diminishes immunogenicity, amplifying the therapeutic index of biologic drugs to new heights of effectiveness.
Biomedical Research: Dive into bio-conjugation and surface modification with 3,6,9,12,15,18,21,24,27-Nonaoxanonatriacontan-1-ol, a fundamental tool for functionalizing nanoparticles and diverse materials. By affixing this PEG derivative to surfaces, researchers navigate the realm of reduced non-specific binding, refining biocompatibility. This aspect is pivotal in the progression of biosensors, diagnostic tools, and a myriad of biomedical devices, accentuating precision and reliability.
Polymer Science: Positioned as a cornerstone in the synthesis of amphiphilic block copolymers, this PEG derivative unlocks realms of self-assembly into structures like micelles and vesicles in aqueous environments. These resulting materials become pioneers in drug delivery, wastewater treatment, and as emulsifying agents in multifarious industrial processes, ushering in an era of innovation and practicality.
Cosmetic Industry: Unveil the transformative prowess of 3,6,9,12,15,18,21,24,27-Nonaoxanonatriacontan-1-ol in the cosmetic domain, serving as an emollient and humectant in skincare formulations. Its adeptness in moisture retention augments skin texture and hydration, nurturing a paradigm shift in skincare efficacy. Furthermore, as a solvent for active ingredients, this compound elevates their permeation and effectiveness in topical applications, paving the way for a new era of cosmetic excellence.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
