Inquiry Basket
| Catalog | Product Name | CAS Number |
|---|---|---|
| BADC-00153 | Chlorotoxin | 163515-35-3 |
| Chlorotoxin (Cltx) is a neurotoxin that was originally isolated from the venom of Leiurus quinquestriatus. Chlorotoxin is a specific ligand of glioma cells. Chlorotoxin binds to Cl- channels (small conductance epithelial chloride channels) in the brain and spinal cord and inhibits Cl- influx. | Inquiry | |
| BADC-00182 | Duocarmycin analog | |
| Duocarmycin analog has cytotoxicity for solid tumor cells that can be used for antibody-drug conjugates (ADCs). Duocarmycins and the analogs acts via binding to the minor groove of DNA and alkylating the nucleobase adenine at the N3 position, which leads to DNA damage and cancer cell death. | Inquiry | |
| BADC-00184 | Tubulysin A | 205304-86-5 |
| Tubulysin A is a novel antibiotic, which exhibits anti-microtubule, anti-mitotic, apoptosis inducer, anticancer, anti-angiogenic, and antiproliferative activity. Tubulysins show very high cytotoxic activity against in vitro and in in vivo tumor models, especially against resistant tumor cell lines. Many representatives of these natural products are several orders of magnitude more potent than other available chemotherapeutics. | Inquiry | |
| BADC-00188 | Auristatin E | 160800-57-7 |
| Auristatin E is a synthetic analog of dolastatin 10. Auristatin E is a highly potent antimitotic agent.Auristatin E inhibits tubulin polymerization. Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity. | Inquiry | |
| BADC-00189 | Ansamitocin P 3' | 66547-09-9 |
| Ansamitocin P 3' is an isomer of Ansamitocin P-3, a potent anti-tumor maytansinoid antibiotic found in Actinosynnema pretiosum, a maytansine analog which displays potent cytotoxicity against the human solid tumor cell lines A-549 and HT-29. | Inquiry | |
| BADC-00253 | Luteolin 7-O-glucoside | 5373-11-5 |
| Cynaroside is a flavone, a flavonoid-like chemical compound. It is a 7-O-glucoside of luteolin. | Inquiry | |
| BADC-00266 | Galantamine hydrobromide | 1953-04-4 |
| Galantamine hydrobromide is a long-acting, centrally active acetylcholinesterase inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors. It prevents β-amyloid-induced apoptosis in SH-SY5Y and bovine chromaffin cells. | Inquiry | |
| BADC-00290 | Lycorine hydrochloride | 2188-68-3 |
| Lycorine is a toxic crystalline alkaloid found in various Amaryllidaceae species, such as the cultivated bush lily , surprise lilies, and daffodils. It may be highly poisonous, or even lethal, when ingested in certain quantities. Symptoms of lycorine toxicity are vomiting, diarrhea, and convulsions. | Inquiry | |
| BADC-00309 | MMAD | 203849-91-6 |
| Monomethyl auristatin D (MMAD), a potent tubulin inhibitor, is a toxin payload and antibody drug conjugate. | Inquiry | |
| BADC-00318 | MMAF | 745017-94-1 |
| Monomethyl auristatin F (MMAF) is a synthetic antineoplastic agent. It is part of some experimental anti-cancer antibody-drug conjugates such as vorsetuzumab mafodotin and SGN-CD19A. In International Nonproprietary Names for MMAF-antibody-conjugates, the name mafodotin refers to MMAF plus its attachment structure to the antibody. | Inquiry | |
| BADC-00324 | MMAE | 474645-27-7 |
| Monomethyl Auristatin E (MMAE) is a synthetic analog of dolastatin 10 that similarly inhibits tubulin polymerization and exhibits potent cytotoxicity. It is commonly conjugated with monoclonal antibodies directed at antigens specific to cancer cells for tumor-directed cytotoxicity. | Inquiry | |
| BADC-00325 | Paclitaxel | 33069-62-4 |
| Paclitaxel is a compound with anti-tumor activity extracted from the Pacific yew tree Taxus brevifolia. Paclitaxel is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells. | Inquiry | |
| BADC-00330 | Irofulven | 158440-71-2 |
| Irofulven is a semisynthetic sesquiterpene derivative of illudin S, a natural toxin isolated from the fungus Omphalotus illudens. Irofulven alkylates DNA and protein macromolecules, forms adducts, and arrests cells in the S-phase of the cell cycle. | Inquiry | |
| BADC-00335 | DC-1 | |
| DC-1 is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates. | Inquiry | |
| BADC-00337 | Seco-Duocarmycin TM | 1142188-60-0 |
| Seco-Duocarmycin TM is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates. | Inquiry | |
| BADC-00339 | DM3 | 796073-54-6 |
| DM3 is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates. | Inquiry | |
| BADC-00340 | PBD dimer | 1222490-34-7 |
| PBD dimer is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates. | Inquiry | |
| BADC-00341 | Seco-Duocarmycin SA | 152785-82-5 |
| Seco-Duocarmycin SA is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates. | Inquiry | |
| BADC-00343 | Seco-Duocarmycin MB | |
| Seco-Duocarmycin MB is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates. | Inquiry | |
| BADC-00346 | Maytansine | 35846-53-8 |
| Maitansine, a cytotoxic agent, inhibits the assembly of microtubules by binding to tubulin at the rhizoxin binding site. | Inquiry |
