ADCs Cytotoxin
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ADCs Cytotoxin

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Catalog Product Name CAS Number
BADC-00323 Sevedindione
Sevedindione presents an antiarrhythmic activity on arrhythmias caused by Aconitine. Inquiry
BADC-00327 Idarubicin 58957-92-9
Idarubicin is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells with IC50 of 3.3 ng/mL. Inquiry
BADC-00328 Topotecan 123948-87-8
Topotecan has been used as a positive control for the identification and analysis of HIF-1α and VEGF inhibitors in human glioma cells under hypoxic conditions. It has also been used for in vitro apoptosis assays in PA317 cells. Inquiry
BADC-00331 Seco-DuocarmycinDME
Seco-Duocarmycin DME is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates. Inquiry
BADC-00332 Seco-DuocarmycinCN 1613286-54-6
Seco-Duocarmycin CN is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates. Inquiry
BADC-00333 Seco-DuocarmycinDMG 1613286-55-7
Seco-Duocarmycin DMG is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates. Inquiry
BADC-00334 Seco-DuocarmycinDMA
Seco-Duocarmycin DMA is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates. Inquiry
BADC-00336 Seco-Duocamycin GA 1613286-59-1
Seco-Duocarmycin GA is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates. Inquiry
BADC-00338 Auristatin T 1799603-53-4
A microtubule-disrupting agent. Inquiry
BADC-00342 Seco-Duocarmycin MA 1613286-57-9
Seco-Duocarmycin MA is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates. Inquiry
BADC-00344 Ducamycin Analog 372954-15-9
Ducamycin Analog is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates. Inquiry
BADC-00345 Tubulysin B 205304-87-6
Tubulysin B is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates. It also has anti-fungal properties. Inquiry
BADC-00362 Duocarmycin B1 124325-93-5
It is produced by the strain of (Pyridamycin) Streptomyces sp. DO-88. It has anti-gram-positive bacteria, gram-negative bacteria and tumor activity. Inquiry
BADC-00363 Aldoxorubicin hydrochloride 480998-12-7
Aldoxorubicin is a prodrug of doxorubicin that binds to serum albumin immediately after administration through an acid-sensitive hydrazone linker and is subsequently transported to tumor tissues where the acidic environment cleaves the linker and facilitates delivery of a tumor-targeted drug payload. Inquiry
BADC-00569 Cryptophycin 1 124689-65-2
Cryptophycin 1, produced by Nostoc sp. GSV 224, is a potent cytotoxic anti-microtubule agent. Cryptophycin 1 can induce cell apoptosis, and has anti-tumor activity and excellent anti-proliferation ability. Inquiry
BADC-00574 Lys-SMCC-DM1 1281816-04-3
Lys-SMCC-DM1 is the active metabolite of DM1. DM1 is a tubulin inhibitor. Inquiry
BADC-00575 (+)-CBI-CDPI1 128300-14-1
(+)-CBI-CDPI1 is an enhanced functional analog of CC-1065. It is also a DNA alkylating agent that acts as an antibody drug conjugate (ADC) toxin. Inquiry
BADC-00576 (+)-CBI-CDPI2 128300-15-2
(+)-CBI-CDPI2 is an enhanced functional analog of CC-1065. It is also a DNA alkylating agent that acts as an antibody drug conjugate (ADC) toxin. Inquiry
BADC-00593 Apaziquone 141304-51-0
Apaziquone is an indolequinone bioreductive prodrug and analog of mitomycin C with potential antineoplastic and radiosensitization activities. Apaziquone is converted to active metabolites in hypoxic cells by intracellular reductases, which are present in greater amounts in hypoxic tumor cells. The active metabolites alkylate DNA, resulting in apoptotic cell death. Inquiry
BADC-00600 Sulfo-PDBA-DM4 1461704-01-7
Sulfo-PDBA-DM4 is a drug-linker conjugate composed of a potent a tubulin inhibitor DM4 and a linker Sulfo-PDBA to make antibody drug conjugate (ADC). Sulfo-PDBA is a gluthatione cleavable linker. Inquiry
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