Inquiry Basket
| Catalog | Product Name | CAS Number |
|---|---|---|
| BADC-00869 | AcLysValCit-PABC-DMAE-SW-163D | 2411007-69-5 |
| AcLysValCit-PABC-DMAE-SW-163D is a drug-linker conjugates for ADC which consists of a natural bis-intercalator, SW-163D, conjugated via an AcLysValCitPABC-DMAE linker. | Inquiry | |
| BADC-00871 | Fmoc-Val-Cit-PAB-Duocarmycin TM | |
| Fmoc-Val-Cit-PAB-Duocarmycin TM is a drug-linker conjugate for ADC by using the antitumor antibiotic, Duocarmycin TM, linked via Fmoc-Val-Cit-PAB. | Inquiry | |
| BADC-01345 | MC-Val-Ala-SG3199 | |
| MC-Val-Ala-SG3199 is a potent cytotoxic compound. It is a potent, selective, irreversible inhibitor with a high reputation in the biomedical field. Its most important significance is in the fight against cancer, especially those that are refractory to traditional treatments. This compound triggers cell death by specifically targeting an enzyme that plays a key role in the ominous expansion and proliferation of tumors. | Inquiry | |
| BADC-01347 | Trastuzumab-MC-MMAE | |
| Trastuzumab-mc-MMAE is an ADC product consisting of an anti-HER2 antibody (Trastuzumab) conjugated to MMAE via an Mc linker. It has been used to treat breast, ovarian and lung cancer by depolymerizing microtubule MOA (mechanism of action). | Inquiry | |
| BADC-01348 | Val-Cit-PAB-MMAE TFA salt | 1608127-32-7 |
| Val-Cit-PAB-MMAE TFA salt, a tubulin polymerase inhibitor, is a drug-linker conjugate for ADC. It contains an ADC linker (peptide Val-Cit-PAB) and a potent tubulin inhibitor MMAE. | Inquiry | |
| BADC-01351 | Maytansinoid B | 1628543-40-7 |
| Maytansinoid B is a kind of ADC Cytotoxin. Maytansinoids are potent microtubule-targeted compounds that inhibit proliferation of cells at mitosis. It is used as the cytotoxic component in antibody-drug conjugates. | Inquiry | |
| BADC-01352 | Glucocorticoid receptor agonist-1 Ala-Ala-Mal | 2166376-51-6 |
| Glucocorticoid receptor agonist-1 Ala Ala Mal is a glucocorticoid that is also an agonist of the glucocorticoid receptor. The glucocorticoid receptor agonist-1Ala Ala Mal can be used to prepare ADC. | Inquiry | |
| BADC-01353 | SG3199 | 1595275-71-0 |
| SG3199 is a cytotoxic DNA minor groove interchain cross-linked PDB dimer. SG3199 is a component of ADC payload Tesirine (SG3249). | Inquiry | |
| BADC-01356 | SC209 | 1977557-86-0 |
| SC209 is an ADC cytotoxic used to synthesize anti-EGFR antibody-drug conjugate ADC. SC209 is a metabolite of STRO-002. | Inquiry | |
| BADC-01357 | PNU-159682 carboxylic acid | 1204819-92-0 |
| PNU-159682 carboxylic acid (compound 53) is a potent ADC cytotoxin encoding a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. PNU-159682 carboxylic acid is involved in protein folding and diverse functions such as cell adhesion, cell signaling, glycoprotein turnover, and roles in inflammation and immune responses. | Inquiry | |
| BADC-01358 | DMEA-PNU-159682 | 1799421-48-9 |
| DMEA-PNU-159682 (molecule D12) is an ADC cytotoxic molecule consisting of neomycin metabolite (MMDX) from liver microsomes and the potent ADC cytotoxin PNU-159682. | Inquiry | |
| BADC-01359 | Anticancer agent 81 | |
| Anticancer agent 81 can induce DNA damage and lead to tumor cell cycle arrest and apoptosis. It is used as a payload to conjugate with trastuzumab to obtain the antibody-drug conjugate (ADC) T-PBA. T-PBA maintained its mode of target and internalization ability of trastuzumab. | Inquiry | |
| BADC-01360 | Daunorubicin citrate | 1884557-85-0 |
| Daunorubicin citrate is a topoisomerase II inhibitor that intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair RNA and protein synthesis. It is used to treat cancer. | Inquiry | |
| BADC-01361 | Duostatin 5 | 2124210-34-8 |
| Duostatin 5 is a cytotoxin similar to dolastatin, and it has the advantages of simple synthesis and stability. | Inquiry | |
| BADC-01362 | BAY 1135626 | 1404071-37-9 |
| BAY 1135626 is used to synthesize BAY 1129980. BAY 1129980 (C4.4A-ADC) is a promising therapeutic candidate for the treatment of NSCLC and other cancers expressing C4.4A. | Inquiry | |
| BADC-01363 | Dideoxy-amanitin | 58255-46-2 |
| Dideoxy-amanitin is an α-Amanitin derivative. α-Amanitin is an extremely toxic bicyclic octapeptide isolated from the death-cap mushroom, Amanita phalloides. As a potent inhibitor of RNA polymerase II, α-amanitin is toxic to eukaryotic cells. | Inquiry | |
| BADC-01364 | TAM470 | 1802498-63-0 |
| TAM470 is an ADC cytolysin, inhibiting tubulin polymerization and depolymerization. TAM470 can be used in the synthesis of OMTX705 that is a novel FAP-targeting ADC demonstrates activity in chemotherapy and pembrolizumab-resistant solid tumor models. | Inquiry | |
| BADC-01365 | S-Me-DM4 | 890654-03-2 |
| S-Me-DM4 is an ADC cytotoxin molecule. It inhibits in vitro polymerization of tubulin and is used in the treatment of advanced breast cancer. | Inquiry | |
| BADC-01366 | Gly-Cyclopropane-Exatecan | 2414254-49-0 |
| Gly-Cyclopropane-Exatecan is a derivative of Exatecan. Exatecan is a drug which is a structural analog of camptothecin with antineoplastic activity and has been used in trials studying the treatment of Sarcoma, Leukemia, Lymphoma, Lung Cancer, and Liver Cancer, among others. | Inquiry | |
| BADC-01367 | Seco-DUBA hydrochloride | 1795733-93-5 |
| Seco-DUBA hydrochloride is the toxin molecule of the ADC drug SYD985. | Inquiry |
