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1-BOC-Azetidine-3-carboxylic acid methyl ester is a non-cleavable ADC linker and also an alkyl chain-based PROTAC linker.
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-01925 | -- | $-- |
1-BOC-Azetidine-3-carboxylic acid methyl ester, a widely utilized chemical intermediate in organic synthesis and drug development, possesses diverse applications. Here are four key applications articulated with heightened perplexity and burstiness:
Pharmaceutical Development: Playing a pivotal role in drug synthesis, this compound acts as a fundamental building block for an array of pharmaceuticals. Researchers harness its potential to innovate new medications by crafting intricate molecular architectures with tailored therapeutic actions. The protective BOC group it offers aids in orchestrating reaction pathways, ensuring the stability of intermediate compounds, and guiding the synthesis towards desired outcomes.
Peptide Synthesis: A cornerstone in peptide assembly, 1-BOC-Azetidine-3-carboxylic acid methyl ester functions as a strategic component in constructing peptide sequences as a shielded amino acid derivative. Its efficacy lies in fostering the formation of peptide bonds without interfering with other reactive sites within the molecule. This attribute renders it invaluable for assembling peptide chains with meticulous precision and unblemished purity, elevating the realm of peptide synthesis to new heights of precision and efficacy.
Medicinal Chemistry: Within the domain of medicinal chemistry, this compound serves as a potent tool for incorporating azetidine ring motifs into drug candidates. The introduction of azetidine moieties can significantly augment the pharmacokinetic and pharmacodynamic profiles of drugs, enhancing their potency and sustainability. This transformative alteration can pave the way for the development of novel therapeutic agents with heightened effectiveness and therapeutic potential, reshaping the landscape of medicinal chemistry through innovative pharmacological design.
Chemical Research: Proving indispensable in diverse chemical research pursuits, 1-BOC-Azetidine-3-carboxylic acid methyl ester is a catalyst for exploring reaction mechanisms and pioneering novel synthetic methodologies. Its distinct molecular structure empowers chemists to venture into uncharted territories of chemical reactions and transformations, driving forward the frontiers of synthetic organic chemistry and fostering a culture of innovation and discovery at the forefront of chemical research.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
