(2-pyridyldithio)-PEG1-hydrazine - CAS 111625-28-6

(2-pyridyldithio)-PEG1-hydrazine - CAS 111625-28-6 Catalog number: BADC-00891

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Category
ADCs Linker
Product Name
(2-pyridyldithio)-PEG1-hydrazine
CAS
111625-28-6
Catalog Number
BADC-00891
Molecular Formula
C7H9NOS2
Molecular Weight
187.28

Ordering Information

Catalog Number Size Price Quantity
BADC-00891 -- $--
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Synonyms
2-(Pyridin-2-yldisulfanyl)ethanol; 2-(2-pyridyldithio)ethanol
Canonical SMILES
C1=CC=NC(=C1)SSCCO
InChI
InChI=1S/C7H9NOS2/c9-5-6-10-11-7-3-1-2-4-8-7/h1-4,9H,5-6H2
InChIKey
PORTXTUJPQINJC-UHFFFAOYSA-N
Density
1.3±0.1 g/cm3
Solubility
10 mm in DMSO
Flash Point
149.3±26.8 °C
Index Of Refraction
1.646
LogP
2.08
PSA
83.72000
Vapor Pressure
0.0±0.7 mmHg at 25°C
Purity
>98%
Shelf Life
0-4°C for short term (days to weeks), or -20°C for long term (months).
Shipping
Room temperature
Storage
-20°C
Pictograms
Corrosive
Signal Word
Danger
Boiling Point
323.3±38.0 °C at 760 mmHg

(2-pyridyldithio)-PEG1-hydrazine, a versatile bifunctional crosslinker, plays a pivotal role in biochemical and pharmaceutical research. Explore its diverse applications, presented with a high degree of perplexity and burstiness.

Protein Conjugation: By harnessing the power of (2-pyridyldithio)-PEG1-hydrazine, scientists intricately link proteins to various molecules or surfaces, creating enduring protein conjugates essential for crafting tailored antibody-drug conjugates (ADCs) for precise cancer therapy. The unique bifunctional nature of this molecule seamlessly attaches to thiol and carbonyl groups, facilitating precise conjugation with unparalleled precision.

Biomolecule Labeling: In the depths of biomolecular research, researchers utilize (2-pyridyldithio)-PEG1-hydrazine for precise labeling of proteins, peptides, or biomolecules with vibrant fluorescent dyes or innovative probes. By selectively reacting with thiol groups, this reagent ensures specific and efficient labeling, enabling detailed studies of biomolecular interactions and cellular processes under the revealing lens of a fluorescence microscope.

Drug Delivery Systems: Venturing into the innovative world of drug delivery, (2-pyridyldithio)-PEG1-hydrazine emerges as a key player in modifying nanoparticles or liposomes with targeted ligands to enhance drug delivery systems. This molecular modification enhances specificity and efficacy, guiding therapeutic agents precisely to designated tissues or cells. With the hydrazine group forming stable bonds under physiological conditions, controlled release of therapeutic agents is assured, revolutionizing drug delivery strategies.

Enzyme Immobilization: In the realm of biosensors and industrial biocatalysis, (2-pyridyldithio)-PEG1-hydrazine serves as a critical tool for immobilizing enzymes onto solid supports. This strategic conjugation not only maintains enzyme activity but also provides a robust attachment to diverse surfaces, enabling the creation of reusable biocatalysts and elevating the efficiency of biochemical assays to new heights of precision and reliability.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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