3-((2,5-Dioxopyrrolidin-1-Yl)oxy)-3-Oxopropyl Acrylate - CAS 1311459-55-8

3-((2,5-Dioxopyrrolidin-1-Yl)oxy)-3-Oxopropyl Acrylate - CAS 1311459-55-8 Catalog number: BADC-00581

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3-((2, 5-Dioxopyrrolidin-1-yl)oxy)-3-oxopropyl acrylate is a linker for antibody-drug-conjugation (ADC).

Category
ADCs Linker
Product Name
3-((2,5-Dioxopyrrolidin-1-Yl)oxy)-3-Oxopropyl Acrylate
CAS
1311459-55-8
Catalog Number
BADC-00581
Molecular Formula
C10H11NO6
Molecular Weight
241.2
3-((2,5-Dioxopyrrolidin-1-Yl)oxy)-3-Oxopropyl Acrylate

Ordering Information

Catalog Number Size Price Quantity
BADC-00581 -- $--
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Description
3-((2, 5-Dioxopyrrolidin-1-yl)oxy)-3-oxopropyl acrylate is a linker for antibody-drug-conjugation (ADC).
Canonical SMILES
C=CC(=O)OCCC(=O)ON1C(=O)CCC1=O
InChI
InChI=1S/C10H11NO6/c1-2-9(14)16-6-5-10(15)17-11-7(12)3-4-8(11)13/h2H,1,3-6H2
InChIKey
QRFYVWLSONYALS-UHFFFAOYSA-N
Shipping
Room temperature, or blue ice upon request.

3-((2,5-Dioxopyrrolidin-1-Yl)oxy)-3-Oxopropyl Acrylate, a functional monomer, has various applications in polymer and material science fields. Here are some key applications of 3-((2,5-Dioxopyrrolidin-1-Yl)oxy)-3-Oxopropyl Acrylate:

Bioconjugation: This acrylate derivative is used in bioconjugation techniques to link biomolecules, such as proteins and peptides, with synthetic polymers. By creating covalent bonds, researchers can develop hybrid materials with unique properties for drug delivery, diagnostics, and tissue engineering. This facilitates the creation of advanced biomaterials that leverage the best properties of both biological and synthetic components.

Surface Modification: 3-((2,5-Dioxopyrrolidin-1-Yl)oxy)-3-Oxopropyl Acrylate can be used to modify surfaces of various substrates, enhancing their wettability, adhesion, and biocompatibility. Through surface grafting or coating, this compound introduces functional groups that can interact with specific target molecules or cells. This has applications in developing advanced medical devices, biosensors, and biocompatible coatings.

Controlled Polymerization: This monomer is employed in controlled polymerization techniques such as atom transfer radical polymerization (ATRP) to synthesize well-defined and functionalized polymers. By precisely controlling the molecular architecture, researchers can tailor the properties of resulting polymers for applications in drug delivery systems, smart materials, and responsive hydrogels. This enables the design of materials with specific functions and behaviors under different environmental conditions.

Crosslinking Agent: In the context of polymer chemistry, 3-((2,5-Dioxopyrrolidin-1-Yl)oxy)-3-Oxopropyl Acrylate serves as an efficient crosslinking agent. By incorporating this monomer into polymer matrices, it can provide additional mechanical strength, thermal stability, and chemical resistance. This is particularly useful in producing high-performance materials for coatings, adhesives, and composite applications.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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