Azetidin-3-ol hydrochloride - CAS 18621-18-6

Azetidin-3-ol hydrochloride - CAS 18621-18-6 Catalog number: BADC-01628

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Azetidin-3-ol hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Category
ADCs Linker
Product Name
Azetidin-3-ol hydrochloride
CAS
18621-18-6
Catalog Number
BADC-01628
Molecular Formula
C3H8ClNO
Molecular Weight
109.55
Azetidin-3-ol hydrochloride

Ordering Information

Catalog Number Size Price Quantity
BADC-01628 -- $--
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Description
Azetidin-3-ol hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms
3-Hydroxyazetidine hydrochloride; 3-Hydroxyazetidine HCl; 3-hydroxy-1-azetidine hydrochloride
IUPAC Name
azetidin-3-ol;hydrochloride
Canonical SMILES
C1C(CN1)O.Cl
InChI
InChI=1S/C3H7NO.ClH/c5-3-1-4-2-3;/h3-5H,1-2H2;1H
InChIKey
UQUPQEUNHVVNKW-UHFFFAOYSA-N
Solubility
DMSO (Slightly), Methanol (Slightly), Water (Slightly)
Melting Point
85-90°C
LogP
0.08130
Appearance
Off-white to light yellow Solid
Signal Word
Danger
Boiling Point
170.7 °C at 760 mmHg

Azetidin-3-ol hydrochloride, a chemical compound renowned for its diverse applications in medicinal chemistry and organic synthesis, is a versatile entity. Explore its applications with a twist of high perplexity and burstiness:

Drug Discovery: With its versatile chemical properties, Azetidin-3-ol hydrochloride plays a pivotal role in the synthesis of various pharmaceuticals, serving as a fundamental building block for beta-lactam antibiotics and other biologically potent compounds. Researchers harness the power of this compound to craft novel drugs, fine-tuning efficacy and safety profiles for enhanced therapeutic outcomes.

Catalysis: Delving into the world of organic reactions, this compound emerges as a prized catalyst, facilitating the synthesis of intricate molecules. Its prowess shines in asymmetric synthesis, yielding enantiomerically pure compounds critical in pharmaceutical realms, where chirality can sway a drug's therapeutic impact. This dramatically blends efficacy with safety considerations in drug design.

Material Science: In the realm of material science, Azetidin-3-ol hydrochloride stands tall, shaping polymers and advanced materials. From crafting novel coatings to revolutionary adhesives and resins, this compound enhances material properties significantly. Its integration into polymer chains elevates mechanical strength, bolsters chemical resistance, and fortifies thermal stability.

Analytical Chemistry: Aiding in the quantification and identification of diverse biological and chemical substances, this compound emerges as a premier reagent in chromatographic and spectroscopic analyses. Unraveling specific compounds in complex mixtures, this application upholds quality control standards, ensuring regulatory compliance in pharmaceutical and chemical sectors.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Historical Records: Azetidin-3-ol hydrochloride
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