6-Maleimidocaproic acid sulfo-NHS - CAS 103848-61-9

6-Maleimidocaproic acid sulfo-NHS - CAS 103848-61-9 Catalog number: BADC-00505

* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

6-Maleimidocaproic acid sulfo-NHS is a small molecule reagent used in the biomedical industry. It is commonly used to modify biomolecules, such as proteins and antibodies, for site-specific conjugation. This compound enables the efficient and stable attachment of drugs, tags, or targeting moieties to these biomolecules, thereby facilitating the development of innovative treatments for a variety of diseases, including cancer and autoimmune diseases.

Category
ADCs Linker
Product Name
6-Maleimidocaproic acid sulfo-NHS
CAS
103848-61-9
Catalog Number
BADC-00505
Molecular Formula
C14H16N2O9S
Molecular Weight
388.35
6-Maleimidocaproic acid sulfo-NHS

Ordering Information

Catalog Number Size Price Quantity
BADC-00505 -- $--
Inquiry
Description
6-Maleimidocaproic acid sulfo-NHS is a small molecule reagent used in the biomedical industry. It is commonly used to modify biomolecules, such as proteins and antibodies, for site-specific conjugation. This compound enables the efficient and stable attachment of drugs, tags, or targeting moieties to these biomolecules, thereby facilitating the development of innovative treatments for a variety of diseases, including cancer and autoimmune diseases.
Synonyms
N-[ε-maleimidocaproyloxy]sulfosuccinimide ester;
IUPAC Name
1-[6-(2,5-dioxopyrrol-1-yl)hexanoyloxy]-2,5-dioxopyrrolidine-3-sulfonic acid
Canonical SMILES
C1C(C(=O)N(C1=O)OC(=O)CCCCCN2C(=O)C=CC2=O)S(=O)(=O)O
InChI
InChI=1S/C14H16N2O9S/c17-10-5-6-11(18)15(10)7-3-1-2-4-13(20)25-16-12(19)8-9(14(16)21)26(22,23)24/h5-6,9H,1-4,7-8H2,(H,22,23,24)
InChIKey
NWHAVGHJSKQCHH-UHFFFAOYSA-N
Appearance
Soild powder
Purity
≥98%
Shipping
Room temperature, or blue ice upon request.
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.

6-Maleimidocaproic acid sulfo-NHS, a highly reactive crosslinking reagent, is extensively utilized in biochemical and biotechnological applications. Here are four key applications of this compound, presented with a high degree of perplexity and burstiness:

Protein Labeling: Serving as a fundamental tool in protein research, 6-Maleimidocaproic acid sulfo-NHS plays a crucial role in covalently attaching fluorescent dyes or other labels to proteins. By interacting with free amine groups on proteins, it facilitates precise and durable labeling essential for various analytical techniques like fluorescence microscopy and flow cytometry. This capability enhances the ability to monitor and analyze protein dynamics within diverse cellular environments, unveiling new dimensions in the exploration of protein function.

Antibody Conjugation: At the heart of therapeutic and diagnostic pursuits, this reagent is pivotal in skillfully conjugating antibodies with drugs, toxins, or enzymes. Through the formation of steadfast thioether bonds with sulfhydryl groups, it ensures targeted and effective delivery of the conjugated molecules. This application stands as a cornerstone in advancing targeted cancer therapies and developing diagnostic assays, ushering in new possibilities for precision medicine and disease detection.

Surface Immobilization: In the realms of biosensing and biochip technologies, 6-Maleimidocaproic acid sulfo-NHS emerges as a critical agent for immobilizing biomolecules onto various surfaces. By establishing a durable linkage between the biomolecule and the sensor surface, it enhances the sensitivity and specificity of biosensing devices. This functionality proves particularly crucial in creating diagnostic tools capable of detecting biomarkers and pathogens, heralding a new era in rapid and accurate disease diagnosis.

Protein-Protein Interaction Studies: Unveiling the intricacies of cellular signaling and molecular dynamics, this crosslinking reagent is invaluable for probing protein-protein interactions. By bridging proteins in close proximity, it empowers researchers to unravel and delineate intricate interaction networks crucial for understanding complex biological processes.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Historical Records: 6-Maleimidocaproic acid sulfo-NHS
Why Choose BOC Sciences?

Customer Support

Providing excellent 24/7 customer service and support

Project Management

Offering 100% high-quality services at all stages

Quality Assurance

Ensuring the quality and reliability of products or services

Global Delivery

Ensuring timely delivery of products worldwide

Questions & Comments
Verification code
Send Inquiry
Verification code
Inquiry Basket