Ala-Ala-Asn-PAB TFA

Ala-Ala-Asn-PAB TFA Catalog number: BADC-01872

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Ala-Ala-Asn-PAB TFA is a peptide cleavable ADC linker for antibody-drug conjugates (ADCs).

Category
ADCs Linker
Product Name
Ala-Ala-Asn-PAB TFA
Catalog Number
BADC-01872
Molecular Formula
C19H26F3N5O7
Molecular Weight
493.43

Ordering Information

Catalog Number Size Price Quantity
BADC-01872 -- $--
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Description
Ala-Ala-Asn-PAB TFA is a peptide cleavable ADC linker for antibody-drug conjugates (ADCs).
IUPAC Name
(2S)-2-[[(2S)-2-[[(2S)-2-aminopropanoyl]amino]propanoyl]amino]-N-[4-(hydroxymethyl)phenyl]butanediamide;2,2,2-trifluoroacetic acid
Canonical SMILES
CC(C(=O)NC(C)C(=O)NC(CC(=O)N)C(=O)NC1=CC=C(C=C1)CO)N.C(=O)(C(F)(F)F)O
InChI
InChI=1S/C17H25N5O5.C2HF3O2/c1-9(18)15(25)20-10(2)16(26)22-13(7-14(19)24)17(27)21-12-5-3-11(8-23)4-6-12;3-2(4,5)1(6)7/h3-6,9-10,13,23H,7-8,18H2,1-2H3,(H2,19,24)(H,20,25)(H,21,27)(H,22,26);(H,6,7)/t9-,10-,13-;/m0./s1
InChIKey
RBSGVTHVRWIZQO-JMHMRROLSA-N
Appearance
Light Yellow to Brown Solid

Ala-Ala-Asn-PAB TFA, a synthetic peptide with diverse applications in bioscience research and development, holds immense potential. Here are four key applications of Ala-Ala-Asn-PAB TFA, presented with high perplexity and burstiness:

Cancer Research: Within the realm of cancer research, Ala-Ala-Asn-PAB TFA emerges as a pivotal player in the development of peptide-centric drug delivery systems tailored to target cancer cells. By intricately conjugating therapeutic agents to this peptide, researchers can boost the selectivity and efficacy of cancer treatments, thereby minimizing collateral damage and amplifying the therapeutic potency of anticancer medications. This innovative strategy reshapes the landscape of cancer therapy by fine-tuning precision and efficacy.

Proteomics: In the intricate realm of proteomics, Ala-Ala-Asn-PAB TFA assumes a crucial role as a tool for unraveling the mysteries of protein identification and quantification. As a standard or control in mass spectrometry analyses, this peptide aids in calibrating instruments and validating experimental findings, ensuring the precision and reproducibility of proteomic data. Its versatility and reliability make it a cornerstone in the pursuit of understanding the complex proteome landscape.

Enzyme Inhibition Studies: Delving into the intricate dynamics of enzyme-substrate interactions and inhibition mechanisms, Ala-Ala-Asn-PAB TFA emerges as a pivotal player. Serving as a model substrate, this peptide facilitates the exploration of enzyme reaction specificity and kinetics, offering crucial insights into the design of novel enzyme inhibitors for therapeutic or industrial use. This foundational knowledge lays the groundwork for the development of targeted interventions that can revolutionize enzyme-based therapies.

Cell Signaling Research: In the dynamic realm of cell signaling, Ala-Ala-Asn-PAB TFA plays a vital role in decoding the intricate language of cellular communication and response to external cues. By integrating this peptide into experimental assays, researchers gain a window into the activation or inhibition of specific signaling pathways, unlocking vital clues for identifying potential drug targets and deciphering the mechanisms underlying various diseases. This peptide's versatility and precision make it a linchpin in unraveling the intricate dance of cellular signaling pathways.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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