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Aldehyde PEG23-thiol is a cleavable 23 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-01199 | -- | $-- |
Aldehyde PEG23-thiol, a functionalized polyethylene glycol molecule, finds diverse applications across scientific and industrial domains. Explore its versatile uses with high perplexity and burstiness:
Bioconjugation: Delving into the realm of biomolecule conjugation, Aldehyde PEG23-thiol emerges as a pivotal player. Its aldehyde group engages specifically with amino groups, forging durable imine bonds, while the thiol component binds adeptly to gold surfaces and other thiol-reactive substances. This dual-functional nature positions it as a versatile linker in crafting biosensors, drug delivery systems, and diagnostic instruments, showcasing its adaptability in diverse applications.
Surface Modification: Within the tapestry of material science, Aldehyde PEG23-thiol serves as an essential agent for surface modification. This versatile compound swiftly alters the surface properties of nanoparticles, polymers, and various materials with finesse. By forming robust bonds with metal surfaces via its thiol group, and providing hydrophilicity and biocompatibility through the PEG chain, it elevates the performance and biocompatibility of medical implants and devices, ushering in a new era of material enhancement.
Drug Delivery: Dive into the intricate realm of drug delivery systems harnessed with Aldehyde PEG23-thiol. Through strategic conjugation of therapeutic molecules to PEGylated surfaces, researchers pave the way for precise targeting of tissues and cells. Enhancing drug solubility, stability, and circulation time in the bloodstream, these engineered systems promise controlled release and targeted delivery, amplifying the therapeutic efficacy and safety profiles, reshaping the landscape of medical interventions.
Nanotechnology: Unveiling the pivotal role of Aldehyde PEG23-thiol in the nanotechnology domain, witness its profound impact on biomedical applications. This compound serves as a linchpin in stabilizing nanoparticles and optimizing their dispersion within biological milieus. Such stabilization underpins targeted imaging, cancer therapy advancements, and the creation of nanodevices for nuanced molecular interactions, driving forward the frontiers of nanoscience and biomedicine.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
