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| Catalog Number | Size | Price | Quantity | ||
|---|---|---|---|---|---|
| BADC-01254 | -- | $-- | Inquiry |
DBCO-SS-PEG4-Biotin is a multifunctional reagent used in bioconjugation techniques. Here are some key applications of DBCO-SS-PEG4-Biotin:
Bioconjugation: DBCO-SS-PEG4-Biotin is frequently used to label biomolecules with biotin, facilitating their subsequent capture or detection using streptavidin-based systems. Its DBCO group allows for selective and efficient conjugation with azide-modified molecules through copper-free Click Chemistry. This makes it ideal for bioorthogonal labeling in live cells or complex biological samples.
Protein Purification: The biotin moiety on DBCO-SS-PEG4-Biotin enables affinity-based purification of proteins. By tagging proteins with this reagent, they can be easily isolated using streptavidin-coated beads or columns. This method is highly effective for purifying proteins without affecting their activity or function, which is critical for downstream applications.
Drug Delivery: DBCO-SS-PEG4-Biotin can be used in the development of targeted drug delivery systems. By biotinylating drug carriers or therapeutic agents, specific targeting can be achieved through biotin-streptavidin interactions. This approach enhances the precision of drug delivery, reducing side effects and increasing efficacy.
Diagnostic Assays: In diagnostic applications, DBCO-SS-PEG4-Biotin is employed to create biotinylated probes and capture molecules. These biotin-tagged entities can bind to streptavidin-coated surfaces, facilitating the detection of target analytes in assays such as ELISA and Western blotting. The use of this reagent thus enhances sensitivity and specificity in diagnostic testing.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
