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Azido-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG6-amine is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity | ||
|---|---|---|---|---|---|
| BADC-01197 | -- | $-- | Inquiry |
Azido-PEG6-amine, a versatile compound prized for its unique chemical properties, finds wide applications in bioconjugation and material science. Here are four key applications of Azido-PEG6-amine presented with high perplexity and burstiness:
Bioconjugation: Azido-PEG6-amine plays a pivotal role in linking biomolecules like proteins and peptides through a sophisticated process known as click chemistry. Its azide group selectively reacts with alkyne-modified partners, forging a robust covalent bond. This application is indispensable for advancing biotherapeutics, diagnostic tools, and imaging agents, pushing the boundaries of molecular connectivity.
Drug Delivery: In the realm of drug delivery research, Azido-PEG6-amine shines in modifying the surfaces of nanoparticles and liposomes. This modification boosts the solubility, stability, and biocompatibility of drug carriers, elevating their efficacy to new heights. Moreover, it facilitates targeted delivery to specific tissues or cells, minimizing off-target effects and maximizing therapeutic impact with surgical precision.
Surface Modification: Azido-PEG6-amine finds its niche in functionalizing surfaces in biosensors and medical devices, offering a gateway to enhanced detection and diagnostic accuracy. By anchoring the compound to a surface, researchers can immobilize diverse molecules like antibodies or enzymes, amplifying the sensitivity and specificity of analytical instruments.
Hydrogel Formation: In the realm of material science, Azido-PEG6-amine takes center stage in crafting hydrogels via a sophisticated click chemistry framework. These tailor-made hydrogels are tailored for applications in tissue engineering and regenerative medicine, boasting tunable physical properties and impeccable biocompatibility. They serve as versatile scaffolds that nurture cell growth and instigate tissue regeneration, offering a gateway to a revolutionary approach in biomedical engineering.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
