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Azido-PEG9-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a non-cleavable 9 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity | ||
|---|---|---|---|---|---|
| BADC-00901 | -- | $-- | Inquiry |
Azido-PEG9-amine, a highly versatile compound in the realms of bioconjugation and molecular biology, boasts a multitude of applications. Here are four key applications of Azido-PEG9-amine, presented with elevated perplexity and burstiness.
Bioconjugation: Azido-PEG9-amine serves as a pivotal agent for linking biomolecules such as proteins, peptides, and nucleic acids together. Its azide group facilitates seamless conjugation via click chemistry reactions, serving as an efficient instrument for the construction of intricate bioconjugates. These diverse conjugates find utility in various realms, including drug delivery, diagnostics, and therapeutic exploration.
Protein Labeling: Within the field of protein analysis, Azido-PEG9-amine assumes a critical role in protein labeling for the purposes of imaging and tracking. By attaching fluorescent dyes or other probes to proteins through the use of Azido-PEG9-amine, researchers can visualize and track protein interactions and localization within cells. This aids in enhancing our comprehension of protein functionalities and cellular processes through a visual lens.
Surface Functionalization: Azido-PEG9-amine emerges as a powerful tool for altering the surfaces of nanoparticles and other materials to bolster their biocompatibility and functionality. This tailored surface modification facilitates precise interactions with target molecules or cells, finding applicability in biosensing, targeted drug delivery, and the coating of medical devices. The enhanced properties of these functionalized surfaces can be tailored to cater to a diverse array of biomedical applications.
Drug Delivery Systems: In the domain of drug delivery research, Azido-PEG9-amine plays a pivotal role in the development of PEGylated drug carriers. The integration of the polyethylene glycol (PEG) chain aids in amplifying the solubility, stability, and circulation time of therapeutic compounds. This augmentation in drug carriers can lead to heightened efficacy and reduced side effects of various drugs by ensuring controlled and targeted delivery mechanisms.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
