Alkyne-PEG2-iodide - CAS 1234387-33-7

Alkyne-PEG2-iodide - CAS 1234387-33-7 Catalog number: BADC-01696

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Alkyne-PEG2-iodide is a click chemistry reagent with terminal alkyne and alkyl iodide groups.

Category
ADCs Linker
Product Name
Alkyne-PEG2-iodide
CAS
1234387-33-7
Catalog Number
BADC-01696
Molecular Formula
C7H11IO2
Molecular Weight
254.07

Ordering Information

Catalog Number Size Price Quantity
BADC-01696 -- $--
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Description
Alkyne-PEG2-iodide is a click chemistry reagent with terminal alkyne and alkyl iodide groups.
Synonyms
3-[2-(2-Iodoethoxy)-ethoxy]-propyne; 1-iodo-2-[2-(prop-2-yn-1-yloxy)ethoxy]ethane
IUPAC Name
3-[2-(2-iodoethoxy)ethoxy]prop-1-yne
Canonical SMILES
C#CCOCCOCCI
InChI
InChI=1S/C7H11IO2/c1-2-4-9-6-7-10-5-3-8/h1H,3-7H2
InChIKey
KRKPKEAEPAZGGU-UHFFFAOYSA-N
Solubility
Soluble in water, polar organic solvents
Appearance
Colorless to yellow oil
Purity
NMR 1H, GC-MS (95%)
Storage
Storage: 24 months after receival at -20 °C in the Dark. Transportation: at room temperature for up to 3 weeks.

Alkyne-PEG2-iodide, a versatile chemical compound, finds myriad applications in bioconjugation and biochemical domains. Here are four key applications of Alkyne-PEG2-iodide, presented with high perplexity and burstiness:

Click Chemistry: Embracing the realm of click chemistry, Alkyne-PEG2-iodide emerges as a cornerstone, facilitating bioorthogonal reactions with finesse. By pairing with azide-functionalized molecules, it orchestrates the precise and exclusive labeling of biomolecules. This intricate dance enables the exploration of protein-protein interactions, delving into the inner workings of cellular processes, and forging paths in diagnostic tool development.

Drug Delivery: Harnessing the PEGylation prowess of Alkyne-PEG2-iodide, researchers delve into the realm of drug delivery systems, where this compound plays a pivotal role. Through strategic attachment to therapeutic agents, it elevates solubility, stability, and bioavailability of drugs, culminating in heightened therapeutic efficacy and mitigated side effects.

Immunoassays: Stepping into the arena of immunoassays, Alkyne-PEG2-iodide takes center stage, driving advancements in diagnostics and clinical research. Its application in modifying antibodies or antigens ushers in a new era of conjugation with reporter molecules like fluorophores or enzymes, enabling the detection of target analytes with precision. Immunoassays emerge as a linchpin in biomarker discovery, paving the way for groundbreaking insights in clinical settings.

Surface Functionalization: A pioneer in surface functionalization, Alkyne-PEG2-iodide empowers the field of biomaterials and nanoparticles. By introducing reactive alkyne groups, it sets the stage for subsequent conjugation with diverse ligands, such as peptides or oligonucleotides, heralding innovations in biosensor development, tissue engineering, and targeted drug delivery systems.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Historical Records: Alkyne-PEG2-iodide
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