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Aminooxy-PEG2-alcohol is a non-cleavable 2-unit PEG ADC linker that is used in the synthesis of antibody conjugated drugs (ADCs). Aminooxy-PEG2-alcohol is also a PROTAC linker, belonging to the PEG class, which can be used to synthesize PROTAC molecules.
| Catalog Number | Size | Price | Quantity | ||
|---|---|---|---|---|---|
| BADC-01012 | -- | $-- | Inquiry |
Aminooxy-PEG2-alcohol, a versatile compound with diverse applications in biomedical and biotechnological research, presents numerous opportunities for advancement. Here are four key applications crafted with high perplexity and burstiness:
Bioconjugation: Functioning as a bioconjugation reagent, Aminooxy-PEG2-alcohol enables the precise attachment of various biomolecules, such as proteins, peptides, or antibodies, to surfaces or other molecules. Its unique reactivity with aldehyde or ketone groups allows for site-specific conjugation, a critical element in the development of diagnostic assays, therapeutic agents, and targeted drug delivery systems. The intricate capabilities of Aminooxy-PEG2-alcohol in facilitating such precise conjugations underscore its significance in the domains of biomedical research and biotechnology.
Protein Labeling: Within the realm of proteomics, Aminooxy-PEG2-alcohol assumes a pivotal role in selectively labeling proteins to track and analyze protein interactions, distribution, and function within biological systems. Through the modification of proteins with this compound, researchers can plunge into the dynamic realm of protein dynamics and interactions, shedding light on the complexities of cellular processes. This application emphasizes the importance of Aminooxy-PEG2-alcohol in unraveling the intricate tapestry of protein-related phenomena within biological systems.
Glycobiology: Aminooxy-PEG2-alcohol finds its niche in the exploration of glycoproteins and glycans, enabling the labeling and identification of crucial carbohydrate moieties. By engaging with oxidized sugars, this reagent empowers scientists to delve into protein glycosylation patterns and their implications in diverse biological functions and diseases. The realm of glycobiology, enriched by the capabilities of Aminooxy-PEG2-alcohol, holds the key to unraveling the enigmas surrounding immune responses, cell signaling, and disease biomarkers, showcasing the compound's significance in unlocking the mysteries of intricate biological systems.
Drug Delivery Development: In the landscape of drug delivery research, Aminooxy-PEG2-alcohol emerges as a pivotal component in attaching therapeutic agents to delivery vehicles like liposomes or nanoparticles through oxime bond formation. This strategic approach ensures the precise release of drugs at the designated target site, minimizing off-target effects and amplifying therapeutic efficacy. The precision and control offered by Aminooxy-PEG2-alcohol in drug delivery systems underscore its role in the advancement of sophisticated and safer drug delivery mechanisms.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
