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Aminooxy-PEG4-alcohol is a non-cleavable 4-unit PEG ADC linker that is used in the synthesis of antibody conjugated drugs (ADCs). Aminooxy-PEG4-alcohol is also a PROTAC linker, belonging to the PEG class, which can be used to synthesize PROTAC molecules.
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-00885 | -- | $-- |
Aminooxy-PEG4-alcohol, a versatile chemical reagent, finds widespread utility in diverse biochemical and pharmaceutical applications. Here are four key applications of Aminooxy-PEG4-alcohol presented with high perplexity and burstiness:
Bioconjugation: A cornerstone of modern biochemistry, Aminooxy-PEG4-alcohol plays a pivotal role in bioconjugation processes involving proteins, peptides, and other biomolecules. By enabling the formation of stable oxime linkages with carbonyl groups, it facilitates the attachment of probes, drugs, or functional groups to biomolecules. This sophistication enhances the exploration of protein function and the advancement of biotherapeutics, paving the way for groundbreaking discoveries in molecular research.
Drug Delivery Systems: The applications of Aminooxy-PEG4-alcohol extend to the realm of advanced drug delivery systems, where its unique properties offer unparalleled advantages. The hydrophilic nature of the PEG moiety enhances the solubility and biocompatibility of drug carriers, while the aminooxy group allows for precise site-specific conjugation. This precision enables targeted and controlled release of therapeutic agents, elevating treatment efficacy while minimizing undesirable side effects, heralding a new era of personalized medicine.
Surface Modification: In the domain of biomaterials and medical devices, Aminooxy-PEG4-alcohol emerges as a game-changing tool for surface modification. Through covalent attachment to surfaces, it confers antifouling properties, mitigating non-specific binding and enhancing biocompatibility. This crucial role in surface modification is instrumental in the development of implantable devices and biosensors characterized by superior performance and extended longevity, revolutionizing healthcare technology.
Glycobiology Research: Within the intricate field of glycobiology, Aminooxy-PEG4-alcohol serves as a valuable asset for labeling and studying glycans and glycoproteins. By reacting with sugar aldehydes to form stable conjugates, it enables researchers to meticulously track and analyze carbohydrate structures and functions, shedding light on complex glycan interactions and disease mechanisms involving glycosylation. This specialized application fuels advancements in understanding intricate biological processes, propelling scientific exploration to new frontiers of knowledge and innovation.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
