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Azido-PEG3-acid is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity | ||
|---|---|---|---|---|---|
| BADC-00881 | -- | $-- | Inquiry |
Azido-PEG3-acid, a versatile compound widely embraced in biochemical and biomedical research, offers a myriad of applications. Here are four key applications of Azido-PEG3-acid presented with high perplexity and burstiness:
Bioconjugation: Embracing Azido-PEG3-acid in bioconjugation practices, researchers unite biomolecules like proteins, peptides, and nucleic acids through specific and efficient coupling reactions facilitated by its azide group. This synergy enables the creation of diverse and multifunctional bioconjugates, unveiling opportunities in diagnostics, therapeutics, and imaging with intricate precision.
Drug Delivery Systems: Within the realm of drug delivery research, Azido-PEG3-acid plays a pivotal role in enhancing and functionalizing drug carriers. By integrating Azido-PEG3-acid into nanoparticles, liposomes, or other delivery systems, researchers elevate solubility, stability, and targeting capabilities, optimizing the efficacy and safety profiles of drug delivery platforms for controlled and site-specific drug release, ensuring utmost precision in therapeutic interventions.
Surface Modification: Delving into surface modification, Azido-PEG3-acid emerges as a transformative tool in enhancing biocompatibility and diminishing non-specific interactions on biomedical devices and materials. Through click chemistry reactions, Azido-PEG3-acid seamlessly attaches to a range of substrates including metals, plastics, and hydrogels, fortifying devices like biosensors and implants against biofouling while amplifying their performance with a strategic finesse.
Proteomics: In the domain of proteomics research, Azido-PEG3-acid carves a niche for itself by enabling the labeling and detection of proteins in intricate biological samples. By incorporating Azido-PEG3-acid modified tags into proteins and employing click chemistry, researchers can affix fluorescent or affinity probes for visualization and purification, unlocking deep insights into protein expression, localization, and interactions.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
