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Azido-PEG4-acid is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Catalog Number | Size | Price | Quantity | ||
|---|---|---|---|---|---|
| BADC-00911 | -- | $-- | Inquiry |
Azido-PEG4-propionic acid, a versatile chemical reagent utilized in bioconjugation and material sciences, presents a myriad of applications. Here are four key applications presented with high perplexity and burstiness:
Bioconjugation and Labeling: Playing a pivotal role in bioconjugation reactions, Azido-PEG4-propionic acid serves as a bridge linking biomolecules like proteins, antibodies, and nucleic acids. The azide group facilitates click chemistry reactions, offering a robust method for attaching fluorescent labels, drugs, or other functional groups. This process aids in the creation of targeted therapeutics, diagnostic tools, and imaging agents, amplifying possibilities in the realms of biomedicine and research endeavors.
Drug Delivery Systems: Leveraging the PEGylation characteristics of Azido-PEG4-propionic acid, this compound emerges as a valuable asset in advancing drug delivery systems. By conjugating drugs to PEG chains through the azide group, solubility is enhanced, drug stability improves, and circulation time in the body is prolonged. The outcome is more efficacious and controlled drug delivery, minimizing adverse effects and optimizing therapeutic outcomes for diverse medical conditions.
Surface Modification: Azido-PEG4-propionic acid finds versatile application in surface modification for introducing functional groups to various materials. This adaptation can be harnessed for crafting bioactive surfaces in tissue engineering, implant coatings, or biosensor applications. The integration of PEG chains improves biocompatibility and diminishes non-specific binding, rendering surfaces conducive to a spectrum of biomedical applications, empowering advancements in healthcare technologies.
Protein Engineering: In the realm of protein engineering, this reagent emerges as a powerful tool for site-specific protein modification. By incorporating an azide functional group at specific sites on a protein, researchers can precisely attach probes or other molecules where needed. This precision opens avenues for in-depth studies on protein function, interactions, and dynamics, propelling progress in structural biology and therapeutic protein design, underpinning crucial developments in the medical and scientific arenas.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
