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| Catalog Number | Size | Price | Quantity | ||
|---|---|---|---|---|---|
| BADC-01237 | -- | $-- | Inquiry |
Boc-amino-PEG3-SSPy is a bifunctional crosslinker with a protected amine group (Boc) and a pyridyl disulfide group (SSPy) separated by a polyethylene glycol (PEG) spacer. Here are some key applications of Boc-amino-PEG3-SSPy:
Protein Conjugation: Boc-amino-PEG3-SSPy is widely used for protein conjugation, enabling the attachment of therapeutic agents, fluorescent probes, or other biomolecules to proteins. The PEG spacer provides flexibility and reduces steric hindrance, improving the stability and function of the conjugated proteins. These conjugates are essential in developing targeted drug delivery systems and diagnostic assays.
Biomolecular Crosslinking: Boc-amino-PEG3-SSPy serves as a versatile crosslinking reagent in the preparation of multifunctional biomolecular assemblies. By linking proteins, peptides, or other biomolecules, it facilitates the study of protein-protein interactions and the creation of complex biomaterials. The reversible nature of the disulfide bond allows for controlled assembly and disassembly.
Surface Modification: Boc-amino-PEG3-SSPy can be used to modify surfaces of biomaterials, enhancing their biocompatibility and functional properties. The PEG spacer helps in reducing non-specific binding and improving bioavailability. Functionalized surfaces are valuable in biosensors, tissue engineering, and medical implants.
Drug Delivery Systems: This compound is employed in the design of advanced drug delivery systems by acting as a linker between drug molecules and delivery carriers. The attachment of Boc-amino-PEG3-SSPy to drugs and their carriers can improve the pharmacokinetics and targeted delivery of therapeutic agents. Such systems are pivotal for improving treatment efficacy and reducing adverse effects.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
