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Boc-cis-L-4-hydroxyproline methyl ester is a non-cleavable ADC linker and also an alkyl chain-based PROTAC linker.
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-01933 | -- | $-- |
Boc-cis-L-4-hydroxyproline methyl ester, a specialized amino acid derivative, finds its application in diverse biochemical and pharmaceutical realms. Here are the key applications of this compound, presented with a high degree of perplexity and burstiness:
Peptide Synthesis: Integral to the synthesis of intricate peptides and proteins, Boc-cis-L-4-hydroxyproline methyl ester acts as a fundamental component in solid-phase peptide synthesis. Its role in incorporating hydroxyproline residues into peptide chains is pivotal for constructing peptides with specific structures and biological functions, particularly those that emulate the complexity of collagen.
Pharmaceutical Development: With a focus on proline-rich drugs and biomolecules, this compound plays an essential role in enhancing the stability, activity, and bioavailability of peptide-based therapeutics. Scientists leverage the unique structure of Boc-cis-L-4-hydroxyproline methyl ester to design and synthesize novel drug candidates for combating various diseases, including cancer and fibrosis, opening new avenues in pharmaceutical innovation.
Structural Biology: In the realm of structural biology, researchers utilize Boc-cis-L-4-hydroxyproline methyl ester to explore protein folding and stability mechanisms. By integrating hydroxyproline into synthetic peptides and proteins, scientists delve into the significance of this amino acid in preserving collagen structure and other protein conformations, offering insights into protein misfolding disorders and guiding the development of therapeutic interventions.
Biomaterials Research: Within the domain of biomaterials research, Boc-cis-L-4-hydroxyproline methyl ester serves as a key component in fabricating hydroxyproline-containing polymers and hydrogels. These materials mimic the extracellular matrix, supporting applications in tissue engineering and regenerative medicine. By enhancing the mechanical properties and biocompatibility of biomaterials, researchers craft advanced scaffolds for tissue repair and regeneration, pushing the boundaries of regenerative medicine forward.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
