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| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-01239 | -- | $-- |
Boc-NH-PEG3-C2-triazole-DBCO-PEG4-VC-PAB-DMEA, a versatile chemical linker, plays a pivotal role in crafting conjugated biomolecules.
Antibody-Drug Conjugates (ADCs): Employing this linker in ADC design and synthesis revolutionizes targeted cancer therapies, fusing antibodies with potent cytotoxic drugs. The linker guarantees stable attachment and controlled drug release within target cells, minimizing off-target effects. This precise delivery mechanism directly impacts cancer cells, elevating treatment precision and efficacy.
Protein Labeling and Modification: Embedded in site-specific protein labeling and modification, Boc-NH-PEG3-C2-triazole-DBCO-PEG4-VC-PAB-DMEA facilitates versatile conjugation to proteins with minimal impact on their biological functions. This capability is instrumental in studying protein interactions, fostering biosensor development, and advancing diagnostic assays.
Controlled Release Systems: The linker’s role in developing controlled drug release systems is paramount, enabling precise release kinetics under specific physiological conditions. By linking therapeutic agents to polymers or nanoparticles, the linker provides a pathway for enhancing therapeutic index and reducing drug-induced side effects through tailored release profiles.
Bioconjugation Reactions: In bioconjugation techniques like click chemistry, Boc-NH-PEG3-C2-triazole-DBCO-PEG4-VC-PAB-DMEA plays a crucial role in linking biomolecules efficiently and flexibly. This innovative approach allows for targeted modifications with high specificity and yield, paving the way for multifunctional diagnostics, imaging agents, and therapeutics for both research and clinical applications.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
