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| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-00698 | 1 g | $1554 |
Boc-Val-Cit-PAB-PNP, a chemical linker pivotal in the development of antibody-drug conjugates (ADCs) for targeted cancer therapy, possesses a myriad of applications.
Antibody-Drug Conjugates (ADCs): Embedded within the intricate design of ADCs, Boc-Val-Cit-PAB-PNP plays a crucial role in delivering cytotoxic drugs exclusively to cancer cells. This strategic linker ensures the precise release of the drug upon arrival at the cancerous tissue, mitigating harm to healthy cells. Such targeted specificity not only amplifies the efficacy of cancer treatments but also enhances their safety profile.
Drug Delivery Systems: Enter the realm of advanced drug delivery systems, where Boc-Val-Cit-PAB-PNP reigns supreme. By leveraging this linker, a realm of possibilities unfolds to optimize the therapeutic index of diverse medications. Conjugating drugs to antibodies or other targeting moieties through this linker enables controlled and localized drug release.
Protein Modification: In the intricate world of protein engineering, Boc-Val-Cit-PAB-PNP emerges as a versatile linker facilitating site-specific protein modification. This innovative capability allows for the conjugation of therapeutic proteins or enzymes to targeting agents, stabilizing molecules, or other functional groups. The resultant bioconjugates retain their biological activity while acquiring novel functionalities, broadening their therapeutic horizons and propelling scientific progress.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
