DAPOA - CAS 2389064-43-9

DAPOA - CAS 2389064-43-9 Catalog number: BADC-01758

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DAPOA is a click chemistry reagent containing an azide group.

Category
ADCs Linker
Product Name
DAPOA
CAS
2389064-43-9
Catalog Number
BADC-01758
Molecular Formula
C5H8N6O3
Molecular Weight
200.16

Ordering Information

Catalog Number Size Price Quantity
BADC-01758 -- $--
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Description
DAPOA is a click chemistry reagent containing an azide group.
IUPAC Name
2-(1,3-diazidopropan-2-yloxy)acetic acid
Canonical SMILES
C(C(CN=[N+]=[N-])OCC(=O)O)N=[N+]=[N-]
InChI
InChI=1S/C5H8N6O3/c6-10-8-1-4(2-9-11-7)14-3-5(12)13/h4H,1-3H2,(H,12,13)
InChIKey
WDGRABVNFATWJY-UHFFFAOYSA-N

DAPOA (Dihydroxyacetone Phosphate Oxidoreductase) stands as a critical enzyme in oxidative carbohydrate metabolism.

Metabolic Engineering: Powering biotechnological advancements, DAPOA plays a pivotal role in metabolic engineering. By manipulating DAPOA activity through overexpression or modulation, researchers can boost the production of valuable biochemicals like ethanol and organic acids within microbial systems. This breakthrough drives the evolution of more sustainable and efficient industrial fermentation processes.

Cancer Research: Delving into cancer biology, DAPOA emerges as a focal point in unraveling altered metabolic pathways within tumor cells. These cells often exhibit heightened glycolytic activity, a phenomenon known as the Warburg effect, where DAPOA serves as a linchpin enzyme. Understanding the intricacies of its regulation offers a gateway to identifying novel therapeutic targets for combating cancer.

Diabetes Research: Within the realm of diabetes research, DAPOA assumes a critical role in deciphering glucose metabolism and insulin signaling. Alterations in DAPOA activity can disrupt glucose homeostasis, contributing to the pathophysiology of diabetes. Researchers delve into the complexities of DAPOA to craft targeted interventions that regulate blood sugar levels and enhance metabolic outcomes for diabetic patients.

Environmental Biotechnology: Unleashing its potential in environmental biotechnology, DAPOA finds application in microbial bioremediation processes aimed at detoxifying environmental pollutants. By harnessing the metabolic pathways involving DAPOA, microbes can be engineered to efficiently break down toxic compounds. This groundbreaking approach is indispensable for the remediation of contaminated environments, fostering ecological rejuvenation and sustainability.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Historical Records: Fmoc-N-(4-azidobutyl)glycine | DAPOA
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