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DOTA-NHS-ester TFA Salt is a linker for affibody molecules and is applied in small animals PET, SPECT, and CT. It can be used to label radiotherapeutic agents or imaging probes for the detection of tumors.
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-01343 | -- | $-- |
DOTA-NHS-ester TFA Salt, a versatile chelating agent in bioconjugation and molecular imaging, finds diverse applications in the following realms:
Radioisotope Labeling: Widely utilized for radiopharmaceutical development, DOTA-NHS-ester TFA Salt acts as a key component in conjugating biomolecules with radioisotopes for both diagnostic imaging and therapeutic interventions. By coupling radioactive metals to peptides or antibodies, scientists craft imaging agents for PET and SPECT scans, enabling visual tracking of drug distribution in the body and facilitating disease diagnosis and treatment monitoring.
Targeted Drug Delivery: In the specialized field of targeted drug delivery, DOTA-NHS-ester TFA Salt plays a pivotal role in labeling therapeutic agents for precise localization within the body. Through conjugation with drugs or nanoparticles, researchers can guide drug carriers to specific tissues or tumor sites, enhancing treatment efficacy while minimizing off-target effects. This strategic delivery mechanism ensures that medications reach their intended destinations with pinpoint accuracy.
MRI Contrast Agents: Enabling the development of contrast agents for magnetic resonance imaging, DOTA-NHS-ester TFA Salt, when chelated with gadolinium, enhances MRI scan contrast, leading to improved visualization of anatomical structures and pathological features. This application proves invaluable for early detection and characterization of tumors and various medical conditions, heightening diagnostic precision and aiding in informed clinical decisions.
Bioconjugation Research: Within the realm of bioconjugation studies, DOTA-NHS-ester TFA Salt serves as an indispensable tool for linking biomolecules together, allowing researchers to create novel biomaterials and explore molecular interactions. By facilitating the attachment of proteins, peptides, or molecules to surfaces, this compound fuels the development of biosensors, immunoassays, and other biotechnological innovations, expanding the frontier of bioconjugation research and its potential applications in various scientific domains.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
