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4-Pentynoyl-Val-Ala-PAB is a click chemistry reagent containing an azide group.
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| BADC-01843 | -- | $-- |
4-Pentynoyl-Val-Ala-PAB, a versatile compound renowned in biochemical and medical research, finds diverse applications. Here are four key applications utilizing high perplexity and burstiness:
Protease Inhibition Studies: Widely employed as a specific inhibitor in protease activity assays, 4-Pentynoyl-Val-Ala-PAB intricately binds to the active sites of target proteases, allowing for a deep dive into the enzyme's kinetics and inhibition mechanisms. This profound knowledge serves as the bedrock for crafting novel therapeutic inhibitors tailored for diseases stemming from protease dysregulation.
Drug Design: In the realm of pharmaceutical research, 4-Pentynoyl-Val-Ala-PAB emerges as a beacon guiding the development of cutting-edge protease inhibitors. Its adaptable structure facilitates enhancements that boost potency and selectivity towards specific proteases. Researchers leverage its potential to innovate and validate new drug candidates targeting a spectrum of conditions, ranging from cancer to infectious diseases, ushering in a new era of therapeutic possibilities.
Chemical Biology: The unique alkyne group present in 4-Pentynoyl-Val-Ala-PAB positions it as a prime contender for bioorthogonal chemistry reactions, notably in click chemistry. By integrating this compound into biological systems, researchers can adorn and monitor specific proteins or processes within live cells. This application stands as a cornerstone for visualizing dynamic cellular processes and investigating intricate protein interactions with unparalleled precision.
Proteomics: Unveiling its prowess in proteomics, 4-Pentynoyl-Val-Ala-PAB emerges as a tool for enriching and unveiling protease substrates alongside their cleavage sites. Through the inhibition of protease activity and the capture of protease-substrate complexes, researchers glean intricate insights into proteolytic pathways, deepening our understanding of the pivotal roles played by proteases in cellular processes and the pathogenesis of diseases.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.
