(E)-2, 5-Dioxopyrrolidin-1-yl 17-bromo-4, 7, 10, 13-tetraoxaheptadec-15-en-1-oate is a PEGn linker for antibody-drug-conjugation (ADC).
Catalog Number | Size | Price | Quantity |
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BADC-00579 | -- | $-- |
(E)-2,5-Dioxopyrrolidin-1-Yl 17-Bromo-4,7,10,13-Tetraoxaheptadec-15-En-1-Oate, a specialized chemical compound with diverse applications, plays a pivotal role in various fields. Here are four key applications presented with high perplexity and burstiness:
Bioconjugation: Utilizing this compound in bioconjugation processes facilitates the linkage of biomolecules like antibodies, proteins, or peptides to diverse tags or drugs. By enhancing the specificity and stability of conjugates, it enables targeted therapy delivery, revolutionizing advanced therapeutic strategies and diagnostic tools development.
Drug Delivery Systems: (E)-2,5-Dioxopyrrolidin-1-Yl 17-Bromo-4,7,10,13-Tetraoxaheptadec-15-En-1-Oate is instrumental in designing drug delivery systems, especially for controlled release formulations. Enabling precise attachment of drug molecules to carrier systems such as nanoparticles or liposomes, it ensures effective and targeted drug release at the action site, enhancing drug efficacy and safety profiles significantly.
Protein Labeling: Within proteomics, this compound aids in protein labeling and modification, facilitating the study of protein interactions, localization, and function. Its reactive groups can covalently bind to specific amino acid residues in proteins, enabling their detection and analysis, thereby shedding light on complex biological systems and disease mechanisms intricacies.
Material Science: In the realm of material science, (E)-2,5-Dioxopyrrolidin-1-Yl 17-Bromo-4,7,10,13-Tetraoxaheptadec-15-En-1-Oate finds application in the functionalization of polymers and surfaces. Its chemical reactivity allows for material modification to introduce new properties like enhanced biocompatibility or antimicrobial activity, driving the development of advanced materials for diverse applications in healthcare, environment, and industry.
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BOC Sciences offers comprehensive services for ADC manufacturing, including antibody modification, linker chemistry, payload conjugation, and formulation development. In particular, our payload-linker customization service offers a convenient and fast raw material channel for many ADC researchers.
BOC Sciences provides one-stop site-specific conjugation services for amino acids, glycans, unnatural amino acids, and short peptide tags. In addition, cysteine conjugation, lysine conjugation, enzymatic conjugation, thio-engineered antibody can also be obtained quickly.
BOC Sciences offers a full range of linkers, including peptide linkers, PEG linkers, click chemistry, PROTAC linkers, non-cleavable linkers, etc. We also provide custom development services for chemically labile linkers and enzymatically cleavable linkers.