(E)-2,5-Dioxopyrrolidin-1-Yl 17-Bromo-4,7,10,13-Tetraoxaheptadec-15-En-1-Oate - CAS 1283658-84-3

(E)-2,5-Dioxopyrrolidin-1-Yl 17-Bromo-4,7,10,13-Tetraoxaheptadec-15-En-1-Oate - CAS 1283658-84-3 Catalog number: BADC-00579

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(E)-2, 5-Dioxopyrrolidin-1-yl 17-bromo-4, 7, 10, 13-tetraoxaheptadec-15-en-1-oate is a PEGn linker for antibody-drug-conjugation (ADC).

Category
ADCs Linker
Product Name
(E)-2,5-Dioxopyrrolidin-1-Yl 17-Bromo-4,7,10,13-Tetraoxaheptadec-15-En-1-Oate
CAS
1283658-84-3
Catalog Number
BADC-00579
Molecular Formula
C17H26BrNO8
Molecular Weight
452.29
(E)-2,5-Dioxopyrrolidin-1-Yl 17-Bromo-4,7,10,13-Tetraoxaheptadec-15-En-1-Oate

Ordering Information

Catalog Number Size Price Quantity
BADC-00579 -- $--
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Description
(E)-2, 5-Dioxopyrrolidin-1-yl 17-bromo-4, 7, 10, 13-tetraoxaheptadec-15-en-1-oate is a PEGn linker for antibody-drug-conjugation (ADC).
Synonyms
(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-(4-bromobut-2-enoxy)ethoxy]ethoxy]ethoxy]propanoate
IUPAC Name
(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-(4-bromobut-2-enoxy)ethoxy]ethoxy]ethoxy]propanoate
Canonical SMILES
C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCC=CCBr
InChI
InChI=1S/C17H26BrNO8/c18-6-1-2-7-23-9-11-25-13-14-26-12-10-24-8-5-17(22)27-19-15(20)3-4-16(19)21/h1-2H,3-14H2
InChIKey
WSWPUIFOGNMUKF-UHFFFAOYSA-N
Shipping
Room temperature, or blue ice upon request.

(E)-2,5-Dioxopyrrolidin-1-Yl 17-Bromo-4,7,10,13-Tetraoxaheptadec-15-En-1-Oate, a specialized chemical compound with diverse applications, plays a pivotal role in various fields. Here are four key applications presented with high perplexity and burstiness:

Bioconjugation: Utilizing this compound in bioconjugation processes facilitates the linkage of biomolecules like antibodies, proteins, or peptides to diverse tags or drugs. By enhancing the specificity and stability of conjugates, it enables targeted therapy delivery, revolutionizing advanced therapeutic strategies and diagnostic tools development.

Drug Delivery Systems: (E)-2,5-Dioxopyrrolidin-1-Yl 17-Bromo-4,7,10,13-Tetraoxaheptadec-15-En-1-Oate is instrumental in designing drug delivery systems, especially for controlled release formulations. Enabling precise attachment of drug molecules to carrier systems such as nanoparticles or liposomes, it ensures effective and targeted drug release at the action site, enhancing drug efficacy and safety profiles significantly.

Protein Labeling: Within proteomics, this compound aids in protein labeling and modification, facilitating the study of protein interactions, localization, and function. Its reactive groups can covalently bind to specific amino acid residues in proteins, enabling their detection and analysis, thereby shedding light on complex biological systems and disease mechanisms intricacies.

Material Science: In the realm of material science, (E)-2,5-Dioxopyrrolidin-1-Yl 17-Bromo-4,7,10,13-Tetraoxaheptadec-15-En-1-Oate finds application in the functionalization of polymers and surfaces. Its chemical reactivity allows for material modification to introduce new properties like enhanced biocompatibility or antimicrobial activity, driving the development of advanced materials for diverse applications in healthcare, environment, and industry.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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